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Topic Editor Godfrey Smith is the founder, director and honorary Chief Scientific Officer of Clyde Biosciences Ltd (UK). The other Topic Editors declare no competing interests with regard to the Research Topic subject.
This completely updated and expanded 2nd Edition provides all the information needed in order to understand the complex molecular, cellular and genetic mechanisms that underlie normal and abnormal cardiac rhythms. Its goal is to help physiologists and clinicians alike develop better preventive and treatment strategies. The respective chapters cover a broad range of topics, including the role of specific ion channels and transporters, gap junctions, intracellular Ca2+ handling in pacemaker activity, impulse conduction, and the activity of atrial and ventricular myocardium. Special emphasis is placed on the unique electrophysiology of specialized pacemaking cells and conducting fibers. In turn...
This open access book is an update of genome editing techniques applied to a range of plants. We discuss the latest techniques and applications to cereals, roots and tubers, oilseed crops, fruit and forest trees, vegetables, legumes and algae including resistance to biotic and abiotic stresses, improved quality, drug production, yield and adaptation to climate change. The regulations in different countries worldwide, the patentibility and the perception by society of the applications of new genomic techniques are examined. This book is written by a multidisciplinary and multisectoral collective of high-profile scientists and other experts belonging to the COST Action network PlantEd, which is mainly European but with contributions from American, Australian, Canadian, Chinese, Indian, Iranian, Pakistani and Peruvian scientists. The book is aimed at a wide audience consisting of students, academics, private and public breeders, other actors in the food and bioeconomy value chains and policy and law makers. This is an open access book.
Divided into three parts, this volume focuses on a summary of how relativity theories were born. It also discusses the ramifications of general relativity, such as black holes, space-time singularities, gravitational waves, the large scale structure of the cosmos, and more. It includes summaries of radical changes in the notions of space and time.
Proceedings of the 10th Hellenic Relativity Conference on Recent Developments in Gravity, held in Kalithea, Chalkidiki, Greece from May 30 to June 2, 2002.
This book focuses on understanding how a megacity like Seoul can be read as a formal architectural composition and not an endless urban sprawl. In a broader sense, the book discusses the dichotomy between city and urbanization: “city” being an architectural problem of bounded forms, while “urbanism” is an infrastructural project of expansion. It is an uncontested reality that urbanization is a continuous global process that has produced nebulous conurbations labeled as megacities. These expand beyond the virtual administrative boundary of any said “city,” producing a discrepancy between an area of administrative control and the real physical condition of human settlement. If ther...
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