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Guided by standard bioscience workflows in high-throughput sequencing analysis, this book for graduate students, researchers, and professionals in bioinformatics and computer science offers a unified presentation of genome-scale algorithms. This new edition covers the use of minimizers and other advanced data structures in pangenomics approaches.
This volume constitutes the refereed proceedings of the 26th International Symposium on String Processing and Information Retrieval, SPIRE 2019, held in Segovia, Spain, in October 2019. The 28 full papers and 8 short papers presented in this volume were carefully reviewed and selected from 59 submissions. They cover topics such as: data compression; information retrieval; string algorithms; algorithms; computational biology; indexing and compression; and compressed data structures.
This book constitutes the refereed proceedings of the 20th Annual Symposium on Combinatorial Pattern Matching, CPM 2009, held in Lille, France in June 2009. The 27 revised full papers presented together with 3 invited talks were carefully reviewed and selected from 63 submissions. The papers address all areas related to combinatorial pattern matching and its applications, such as coding and data compression, computational biology, data mining, information retrieval, natural language processing, pattern recognition, string algorithms, string processing in databases, symbolic computing and text searching.
The papers contained in this volume were presented at the 19th Annual S- posium on Combinatorial Pattern Matching (CPM 2008) held at the University of Pisa, Italy, June 18–20, 2008. All the papers presented at the conference are originalresearchcontributions on computational pattern matching and analysis. They were selected from 78 submissions. Each submission was reviewed by at least three reviewers. The committee decided to accept 25 papers. The programme also includes three invited talks by Daniel M. Gus?eld from the University of California, Davis, USA, J. Ian Munro from the University of Waterloo, Canada, and Prabhakar Raghavan from Yahoo! Research, USA. The objective of the annual CP...
One of Springer’s renowned Major Reference Works, this awesome achievement provides a comprehensive set of solutions to important algorithmic problems for students and researchers interested in quickly locating useful information. This first edition of the reference focuses on high-impact solutions from the most recent decade, while later editions will widen the scope of the work. All entries have been written by experts, while links to Internet sites that outline their research work are provided. The entries have all been peer-reviewed. This defining reference is published both in print and on line.
This book covers algorithmic problems in big data applications, presenting solutions over hierarchical-memory systems along with pseudocode.
The papers contained in this volume were presented at the 13th Annual S- posium on Combinatorial Pattern Matching, held July 3–5, 2002 at the Hotel Uminonakamichi, in Fukuoka, Japan. They were selected from 37 abstracts s- mitted in response to the call for papers. In addition, there were invited lectures by Shinichi Morishita (University of Tokyo) and Hiroki Arimura (Kyushu U- versity). Combinatorial Pattern Matching (CPM) addresses issues of searching and matching strings and more complicated patterns such as trees, regular expr- sions, graphs, point sets, and arrays, in various formats. The goal is to derive n- trivial combinatorial properties of such structures and to exploit these pro...
Data compression is mandatory to manage massive datasets, indexing is fundamental to query them. However, their goals appear as counterposed: the former aims at minimizing data redundancies, whereas the latter augments the dataset with auxiliary information to speed up the query resolution. In this monograph we introduce solutions that overcome this dichotomy. We start by presenting the use of optimization techniques to improve the compression of classical data compression algorithms, then we move to the design of compressed data structures providing fast random access or efficient pattern matching queries on the compressed dataset. These theoretical studies are supported by experimental evidences of their impact in practical scenarios.
This book constitutes the proceedings of the 22nd Annual Conference on Research in Computational Molecular Biology, RECOMB 2018, held in Paris, France, in April 2018. The 16 extended and 22 short abstracts presented were carefully reviewed and selected from 193 submissions. The short abstracts are included in the back matter of the volume. They report on original research in all areas of computational molecular biology and bioinformatics.
In the post-genomic era, a holistic understanding of biological systems and p- cesses,inalltheircomplexity,is criticalincomprehendingnature’schoreography of life. As a result, bioinformatics involving its two main disciplines, namely, the life sciences and the computational sciences, is fast becoming a very promising multidisciplinary research ?eld. With the ever-increasing application of lar- scalehigh-throughputtechnologies,suchasgeneorproteinmicroarraysandmass spectrometry methods, the enormous body of information is growing rapidly. Bioinformaticians are posed with a large number of di?cult problems to solve, arising not only due to the complexities in acquiring the molecular infor- ti...