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Development of an effective anticancer therapeutic necessitates the selection of cancer-related or cancer-specific pathways or molecules that are sensitive to intervention. Several such critical yet sensitive molecular targets have been recognized, and their specific antagonists or inhibitors validated as potential therapeutics in preclinical models. Yet, majority of anticancer principles or therapeutics show limited success in the clinical translation. Thus, the need for the development of an effective therapeutic strategy persists.
“Altered energy metabolism” in cancer is one of the earliest known biochemical phenotypes which dates back to the early 20th century. The German ...
TI has received honoraria from Eisai as a consultant and grants or funding to his institution from Novartis. TI participated in congress for which travel and accommodations were paid by Ipsen, Pharmamar, and Novartis.
Endometriosis is a common and serious disease that is estimated to cost the world economy $9.7 billion a year. Most of these costs come from lost productivity at work. As such, it is important to help women receive earlier diagnosis and more effective treatment. This book presents a comprehensive overview of endometriosis, including information on molecular diagnostics and imaging methods for early detection as well as new, less-invasive treatments that preserve women’s fertility.
As Christianity in Africa is witnessing an unprecedented growth in membership, the author argues that in order to sustain its momentous growth and deepen the faith particularly among Catholics, the Church needs to acculturate an African model that resonates with Africans’ religiosity, cultural consciousness and worldview. The author contends that the model of the Church as the Extended family of God is best suited for an African ecclesiology and deepening the faith of African Christians.
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