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This book, now in an extensively updated and expanded third edition, offers important insights into polymyalgia rheumatica (PMR) and giant cell arteritis (GCA), providing an overview of their pathophysiology, genetics, immunology, and endocrinological mechanisms but above all presenting the state of the art in diagnosis and treatment. Both PMR and GCA are diseases of advanced age. Early diagnosis and treatment can save one of the most precious senses – vision. In this book, the role of imaging techniques is thoroughly examined, with particular attention to ultrasonography and FDG PET. All aspects of management of both diseases are discussed, including the current use of glucocorticoids, th...
A guide to over ... international nonprofit membership organizations including multinational and binational groups, and national organizations based outside the United States, concerned with all subjects or areas of activity.
In the present monograph, we offer current insights into polymyalgia rheumatica and giant cell arthritis. Both diseases are typical for advanced age, and their incidences increase with aging. Both diseases are a center point of interest not only for rheu- tologists, gerontologists, ophthalmologists or neurologists, but also for general prac- tioners. Early diagnosis and rapid treatment, mainly with glucocorticoids can save one of the most precious senses-vision. Damage to other organs (heart, aorta, co- nary arteries, liver, lungs, kidneys), which are supplied by the arteries affected by ischemic syndrome in the setting of giant cell arthritis, has serious consequences as well. Late diagnosi...
Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi cian's opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, qu...
A practical, full-color reference on the major medical and minmally invasive approaches to managing patients with common and rare vascular diseases Vascular Medicine is one of the first truly comprehensive texts to provide a medically-focused, as opposed to surgically focused, approach to the management of vascular diseases. Presented in full color, with extensive illustrations and practical, clinically-oriented text, the book covers all major conditions such as inflammatory disease, portal hypertension, and granulamatosis. Reflecting an interdisciplinary approach, the author team represents all major specialties represented in the book (outpatient medicine, vascular medicine, cardiology, and radiology).
The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area. - Comprehensively reviews all aspects of heparin and heparan sulfate research - Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work - Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners
Varicose veins and telangiectasias are the most frequent presentations of chronic venous disease. In Western societies, they affect almost one person out of two. A disease of aging, chronic venous disease is almost as frequent in men as in women. The high prevalence of the disease, the suffering it engenders, and the serious progressive stages that may occur, together with its impact on healthcare costs, call for attentive and informed management by the physician. The highly informative review affords the practitioner a clear, objective, and practical view of phlebology. Thanks to the multidisciplinary experience of the authors, the book rigorously defines varicose veins and telangiectasias ...