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Evolutionary Biology
An integrative view of the evolution of genetics and the naturalworld Even in this advanced age of genomics, the evolutionary processof unicellular and multicellular organisms is continually indebate. Evolutionary Biology, Cell–Cell Communication, andComplex Disease challenges current wisdom by using physiology topresent an integrative view of the nature, origins, and evolutionof fundamental biological systems. Providing a deeper understanding of the way genes relate to thetraits of living organisms, this book offers useful informationapplying evolutionary biology, functional genomics, and cellcommunication studies to complex disease. Examining the 4.5billion-year evolution process from en...
Evolution, the Logic of Biology
By focusing on the cellular mechanisms that underlie ontogeny, phylogeny and regeneration of complex physiologic traits, Evolution, the Logic of Biology demonstrates the use of homeostasis, the fundamental principle of physiology and medicine, as the unifying mechanism for evolution as all of biology. The homeostasis principle can be used to understand how environmental stressors have affected physiologic mechanisms to generate condition-specific novelty through cellular mechanisms. Evolution, the Logic of Biology allows the reader to understand the vertebrate life-cycle as an intergenerational continuum in support of effective, on-going environmental adaptation. By understanding the princip...
Evidence-Based Evolutionary Medicine
A groundbreaking, evidence-based text to the growing field of evolutionary medicine Evidence-Based Evolutionary Medicine offers a comprehensive review of the burgeoning field of evolutionary medicine and explores vital topics such as evolution, ecology, and aging as they relate to mainstream medicine. The text integrates Darwinian principles and evidence-based medicine in order to offer a clear picture of the underlying principles that reflect how and why organisms have evolved on a cellular level. The authors—noted authorities in their respective fields—address evolutionary medicine from a developmental cell-molecular perspective. They explore the first principles of physiology that exp...
Novel Aspects of PTHrP Physiopathology
The idea of this book is to attempt to provide an appropriate ground for the discussion of modern PTHrP-related issues, and for the consideration of attentive speculation and comments on current work. It is designed to intersect all the usual lines of disciplines, providing a site for presenting pertinent investigations and for discussing critical questions relevant to the entire field, thus seeking to develop a new focus and new perspectives for all those concerned with PTHrP and its pathobiology.
Early-life Environmental Exposure and Disease
This book offers valuable insights into the latest concepts and findings from epidemiologic, clinical and basic studies in the burgeoning area of early-life environmental exposure and diseases. The book is divided into five parts, starting with an overview of environmental exposure measurement and evaluation, followed by a review of the effects of exposure to various substances like tobacco smoke, pesticides and metals as well as stress on offspring’s health. It then discusses the developmental origins of a range of childhood diseases that affect growth, neural development and the immune system, and highlights the importance of longitudinal studies that measure exposure at potentially sensitive time points during childhood. It also provides up-to-date evidence of the intergenerational/transgenerational effects of early-life environmental exposure, especially via genetic and epigenetic pathways. Allowing readers to gain a thorough understanding of the predominating aspects of early-life environmental exposure and diseases, the book also provides a basis for developing environmental and health policies that could have wide and long-term impacts on human health.
Bronchopulmonary Dysplasia
This book provides a comprehensive framework for treatment and management of bronchopulmonary dysplasia. In recent years great strides have been made toward understanding the pathogenesis and clinical aspects of BPD, which is the most common chronic lung disease affecting infants. This one-stop resource is written by leading scientists and clinicians in the field, and chapters discuss the most recent developments in the basic scientific, translational, and clinical characteristics of the disease. Topics such as hyperoxia, pre- and post-natal inflammation, and genetics and biomarkers of BPD are included, as well as non-invasive ventilation techniques, nutrition, and radiology applications from pre-term birth to adulthood. The book closes with an in-depth look at emerging therapeutic options for prevention of BPD. Bronchopulmonary Dysplasia is an essential volume for all neonatologists, pediatric pulmonologists, and scientists interested in developmental disorders of the lung.
Vitamin D and the Lung
Vitamin D deficiency is a worldwide problem and many associations with diseases are being discovered. Recently, there has been an interest in the role that vitamin D plays in the inception and progression of lung disease. Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders. Divided into three sections, the first section of the book delivers a review of how vitamin D deficiency emerged in human populations, and gives a perspective on how humans evolved to maximize the efficiency of production of vitamin D. The second section of the book reviews aspects of vitamin D mechanisms on...
Avery's Neonatology
Revised and updated by a new editorial team, the Sixth Edition of this text will remain the leading reference on the clinical care of the newborn. It provides complete, authoritative information on the biology of the newborn and the pathophysiology and management of diseases during the neonatal period. This edition has five new chapters on the role of telemedicine in neonatology, the impact of labor and delivery on the fetus, fetal determinants of adult disease, breast feeding, and control of breathing and apnea. Also included is a full-color insert illustrating key signs and symptoms, selected imaging techniques, and dermatologic conditions.
Thrive with Diabetes
Sincere, well considered, and right on the money, this important self-empowerment health and wellness guide helps diabetics take control of their lifestyle and diet challenges “ and their future.
