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Hazardous Reagent Substitution
Showing how the pharmaceutical industry has adopted green chemistry, this book is of interest to industrialists working in pharmaceuticals and researchers working in green chemistry.
Organic Synthesis
A collection of Douglass Taber's columns originally published between 2013 - 2015 at www.organicchemistry.org
Innovative Catalysis in Organic Synthesis
C-H, C-O, C-C, and C-Heteroatom bond forming processes by using metal-ligand approaches for the synthesis of organic compounds of biological, pharmacological and organic nanotechnological utility are the key areas addressed in this book. Authored by a European team of leaders in the field, it brings together innovative approaches for a variety of catalysis reactions and processes frequently applied in organic synthesis into a handy reference work. It covers all major types of catalysis, including homogeneous, heterogeneous, and organocatalysis, as well as mechanistic and computational studies. Special attention is paid to the improvements in efficiency and sustainability of important catalytic processes, such as selective oxidations, hydrogenation, and cross-coupling reactions, and to their utilization in industry. The result is a valuable resource for advanced researchers in both academia and industry, as well as graduate students in organic chemistry aiming for chemo-, regio- or stereoselective synthesis of organic compounds by using novel catalytic systems.
Organic Synthesis
This book is a useful field guide for the practicing organic chemist and a rich introduction for the student. Functional group transformations, new catalysts, and improved enantioselective methods are included. Many current total syntheses are also discussed in detail.
Hydrolysis, Oxidation and Reduction
Catalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech catalysts, which add enormously to the repertoire of synthetic possibilities. However, catalysts are occasionally capricious, sometimes difficult to use and almost always require both skill and experience in order to achieve optimal results. This series aims to be a practical help for advanced undergraduate, graduate and postgraduate students, as well as experienced chemists in industry and academia working in organic and organometallic synthesis. The series features: * Tested and validated procedures. * Authoritative reviews on clas...
Regio- and Stereo-Controlled Oxidations and Reductions
Volume 5 in the Catalysts for Fine Chemical Synthesis series describes new procedures for the regio- and stereo-controlled transformations of compounds involving oxidation or reduction reactions. It describes a wide range of catalysts, including organometallic systems, biocatalysts and biomimetics. This volume also includes descriptions of a variety of conversions, including: Baeyer-Villiger oxidations; Epoxidation reactions; Hydroxylation reactions; Oxidation of alcohols to aldehydes, ketones and carboxylic acids; Reduction of ketones; and Reduction of alkenes including α, β-unsaturated carbonyl compounds. The book will be an important text for practising synthetic organic chemists in industry and academia. Protocols are written in a standard format by the authors who have discovered them Hints, tips and safety advice (where appropriate) is given to ensure that the procedures are reproducible Indications are given as to the range of starting materials used and, where appropriate, comparisons to alternative methodology Includes relevant references to the primary literature.
Asymmetric Hydrogenation and Transfer Hydrogenation
Asymmetric Hydrogenation and Transfer Hydrogenation Discover the latest developments in homogeneous asymmetric (transfer) hydrogenation with this up-to-date resource Asymmetric Hydrogenation and Transfer Hydrogenation delivers a current and cutting-edge investigation of homogenous asymmetric hydrogenation and transfer hydrogenation reactions of prochiral substrates by using organometallic catalysts (like ruthenium, rhodium, iridium, iron, and copper) and organic catalysts. Distinguished researchers and editors Virginie Ratovelomanana-Vidal and Phannarath Phansavath also offer readers a comprehensive walkthrough of substituted ketones through dynamic kinetic resolution, as well a presentation...
Science of Synthesis: Catalytic Reduction in Organic Synthesis
Catalytic reductions are among the most used synthetic transformations, and the past 15 years have seen great progress in this field. Science of Synthesis: Catalytic Reduction in Organic Synthesis includes the latest developments, as well as selective coverage of more well-established methods. Both heterogeneous and homogeneous catalytic systems are covered, and enantioselective methodology is well represented. There is a focus on the use of metal nanoparticles, both in suspension as well as on solid supports. Furthermore, the advent of research on the conversion of renewable resources into fuels and chemicals has given a great impetus to the field, as deoxygenations are often the first step in the conversion of biomass and this can often be achieved using hydrogenation or hydrogenolysis reactions. Scope, limitations, and mechanism of the reactions are discussed and key experimental procedures are included.
Modern Reduction Methods
With its comprehensive overview of modern reduction methods, this book features high quality contributions allowing readers to find reliable solutions quickly and easily. The monograph treats the reduction of carbonyles, alkenes, imines and alkynes, as well as reductive aminations and cross and heck couplings, before finishing off with sections on kinetic resolutions and hydrogenolysis. An indispensable lab companion for every chemist.
