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Vertebrate Photoreceptors
This book provides a series of comprehensive views on various important aspects of vertebrate photoreceptors. The vertebrate retina is a tissue that provides unique experimental advantages to neuroscientists. Photoreceptor neurons are abundant in this tissue and they are readily identifiable and easily isolated. These features make them an outstanding model for studying neuronal mechanisms of signal transduction, adaptation, synaptic transmission, development, differentiation, diseases and regeneration. Thanks to recent advances in genetic analysis, it also is possible to link biochemical and physiological investigations to understand the molecular mechanisms of vertebrate photoreceptors wit...
Development, structure and function of vertebrate retinas: A virtual festschrift for Prof. Steve Massey
This is a remarkable time to study the vertebrate retina, either as a model for the brain or to understand the first steps in vison. We have known about the diversity of retinal neurons and glia for more than one hundred years, and we are now extending these findings and making new discoveries about retinal cell types by analyzing gene expression in single cells. We have made significant progress toward our ultimate goals of describing the neural circuits in the retinas at the level of connections between identified populations of neurons and understanding neuronal and glial cell function at the molecular level. We have also made great strides toward understanding retinal development and the...
Neuroimmune Pharmacology
The second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.
Redox-Signaling in Neurodegenerative Diseases: Biomarkers, Targets, and Therapies
Redox homeostasis results from the balance between the production of reactive species (e.g. ROS, RNS, etc) and their detoxification by endogenous or exogenous antioxidants. ROS play several important physiological roles, however, their excessive production or impaired detoxification is associated with oxidative stress and cellular injury. Importantly, oxidative damage to vulnerable central nervous system (CNS) cells is a common pathological feature of several neurodegenerative diseases. Antioxidants have been considered as attractive potential therapeutic agents to prevent or halt disease progression but the clinical efficacy of antioxidant treatment strategies is still marginal. Improvement...
Methods for Synaptic Interrogation
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Ash, Ashe, Stillwell
Jesse Ash was born about 1784 in Virginia. He married Mary Huffman and died in Jackson County, North Carolina about 1859.
