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The authors of this 2004 volume consult Chinese and Western archival materials to examine the Chinese War of Resistance against the Japanese in the Shanghai area. They argue that the war in China was a nationalistic endeavour carried out without an effective national leadership. Wartime Chinese activities in Shanghai drew upon social networks rather than ideological positions and these activities cut across lines of military and political divisions. Instead of the stark contrast between heroic resistance and shameful collaboration, wartime experience in the city is more aptly summed up in terms of bloody struggles between those committed to normalcy in everyday life and those determined to bring about its disruption through terrorist violence and economic control. The volume offers an evaluation of the strategic significance of the Shanghai economy in the Pacific War. It also draws attention to the feminisation of urban public discourse against the backdrop of intensified violence. The essays capture the last moments of European settlements in Shanghai under Japanese occupation.
These Proceedings gather outstanding papers submitted to the 2014 SAE-China Congress, the majority of which are from China, the most dynamic car market in the world. The book covers a wide range of automotive topics, presenting the latest technical achievements in the industry. Many of the approaches it presents can help technicians to solve the practical problems that most affect their daily work.
Immunotherapy has revolutionized the treatment of malignancies. Targeting of immune checkpoints cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has led to improving survival in a subset of patients. Despite their remarkable success, clinical benefit remains limited to only a subset of patients. A significant limitation behind these current treatment modalities is an irregularity in clinical response, which is especially pronounced among checkpoint inhibition. Currently, relevant predictors of cancer immunotherapy response include microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR), expression of PD-L1, tumor mutati...
Reinforcement Learning is a promising tool to automate controller tuning. However, significant extensions are required for real-world applications to enable fast and robust learning. This work proposes several additions to the state of the art and proves their capability in a series of real world experiments.
Respiratory diseases share the most complex processes, including various immune reactions, abnormal embryological development, air- or blood-flow mechanical dysfunction, carcinogenesis, and fibrotic proliferation. Metabolic reprogramming has been identified as one of the most critical pathogenic mechanisms for cellular functional maintenance and adaptation under different etiologies. Therefore, intervention targeting metabolic pathways provide a novel therapeutic strategy.