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First multi-year cumulation covers six years: 1965-70.
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Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs. The chapters are written by leading experts and cover development of nimesulide, including synthesis and production, introduction, and approved uses and applications, followed by pharmacokinetics and toxicological properties, adverse reactions and their mechanisms.
Muscle Pain Syndromes and Fibromyalgia: Pressure Algometry for Quantification of Diagnosis and Treatment Outcome represents a new approach by quantifying the diagnosis and outcome assessment of musculoskeletal pain by pressure algometry. Such quantitative studies are useful in daily practice of pain management as well as in research and medicolegal documentation. The basic question of whether or not pressure sensitivity has reached an abnormal level can be answered quantitatively. Findings of different clinicians can be compared in numbers. The efficacy of different therapeutic procedures can be assessed numerically immediately after injections or physical therapy. Long-term effects of pain ...