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Somatostatin
Montreal has had a longstanding interest in somatostatin. Two years ago when the final planning began for the International Con gress of Endocrinology in Quebec City in July 1984, we seized the op portunity for having a separate Satellite Symposium on somatostatin here in Montreal. We felt that after a decade of uniformly vigorous growth in somatostatin research, the opportune moment had arrived for a review of the most significant past developments and for setting the directions for the future. Knowing the futility of trying to cover every aspect of the burgeoning somatostatin field in a two day scientific program, we opted for a detailed analysis of selected areas which were reasonably mat...
Neurotherapeutics
Neuroscience's inherent complexity and rapid growth mean that no one can keep abreast of all the changes across the field. We each bring a necessarily narrow perspective. Neurotherapeutics: Emerg ing Strategies is an attempt to provide some diverse perspectives within the hunt for new drugs to treat central nervous system diseases. The book's premise is that the search for new drugs is based on an understanding ofboth clinical and basic sciences. Neurotherapeu tics: Emerging Strategies begins with psychiatry and concludes with neurological disorders. Each chapter examines a disease, including clinical features and existing treatments, but the emphasis is on current concepts of underlying cau...
Somatostatin
- Each chapter is written by expert(s) active in somatostatin research (experimental and/or clinical) - It will serve as the only single one-stop source of the most up to date information on the basic and clinical aspects of the biology of somatostatin
Somatostatin
The discovery of hypothalamic factors that inhibited growth hormone secretion and of pancreatic factors that inhibited insulin secretion were the first clues to the existence of somatostatin. During the course of efforts to isolate growth hormone releasing factor, Krulich, McCann and Dhariwal found that hypothalamic extracts contained a potent inhibitor of growth hormone secretion. They postulated that growth hormone secretion was under a dual control system, one inhibitory and the other excitatory (I) . In studies being carried out at about the same time, Hellman and Lernmark found a factor in pancreatic extracts that inhibited insulin secretion (2). They postulated that islet cell function...
Research Grants
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Clinical Neuroendocrinology
Clinical Neuroendocrinology covers the clinical significance of the advances made in the understanding of relationships between the actions of neurotransmitters and the hypothalamic control of pituitary secretions. This book contains 24 chapters that examine the interactions of target gland secretions with the effects of hypothalamic and pituitary hormones. This book begins with a discussion of the physiological regulation and clinical applications of thyrotropin-stimulating hormone and thyrotropin-releasing hormone. The subsequent chapters are devoted to neuroendocrine aspects, secretion, regulation, and analysis of gonadotropin and gonadotropin-releasing hormone. Other chapters explore the...
