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Cholera is a frightening disease. Victims are wracked by stomach cramps and suffer intense diarrhoea. Death can come within hours. Though now seeming a distant memory in Europe, which suffered several epidemics in the 19th century before John Snow identified the link with water, it is still a serious threat in many parts of the world - Zimbabwe is a recent example. Snow's discovery was one of the great breakthroughs of epidemiology and a wonderful story from the history of science. Later came the discovery of the culprit organism - Cholera vibrio - understanding of its life cycle, and the development of a vaccine. But the problem of cholera has not disappeared. This book tells the story of c...
This proceedings volume gathers selected, peer-reviewed works presented at the Polynomial Rings and Affine Algebraic Geometry Conference, which was held at Tokyo Metropolitan University on February 12-16, 2018. Readers will find some of the latest research conducted by an international group of experts on affine and projective algebraic geometry. The topics covered include group actions and linearization, automorphism groups and their structure as infinite-dimensional varieties, invariant theory, the Cancellation Problem, the Embedding Problem, Mathieu spaces and the Jacobian Conjecture, the Dolgachev-Weisfeiler Conjecture, classification of curves and surfaces, real forms of complex varieties, and questions of rationality, unirationality, and birationality. These papers will be of interest to all researchers and graduate students working in the fields of affine and projective algebraic geometry, as well as on certain aspects of commutative algebra, Lie theory, symplectic geometry and Stein manifolds.
Though cholera is an ancient disease, its perennial occurrence in several parts of the world has attracted many researches to find ways and means to combat the disease. The prevailing seventh pandemic cholera is dominating since 1961, but the dimension of the disease has taken several silhouettes, as the genetic structure and functions of the Vibrio cholerae has changed to a great extent. Several recent studies have shown that transformation of the pathogen at the molecular level has ameliorated several cholera outbreaks and epidemics of with successive new clones of V. cholerae. This comprehensive compilation, written by eminent international researchers reviews the epidemiology of cholera ...
This volume describes the structure and function of bacterial toxins and presents a comprehensive review of virulence factors, providing recent information concerning cell physiology and biochemistry, as well as new toxin tools for experimental studies and clinical therapy. A wide variety of toxic proteins, including the toxins that cause diptheria, cholera, pertussis, shigellosis, tetanus, botulism and anthrax, are discussed.;The work is aimed at microbiologists, biochemists, endocrinologists, toxicologists, infectious disease specialists, pathologists, public health officials, and upper-level undergraduate and graduate students in these disciplines.
It is surprising how little is actually known about the fate of wastewater bacteria once they enter the sea. This wide-ranging work is one of the first to unravel the mechanisms determining bacterial sensitivity or survival under these conditions.