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With applications across chemistry, physics and medicine, nuclear magnetic resonance is a proven, uniquely versatile and powerful spectroscopic technique. The success of NMR and its constant redevelopment means that the literature is vast and wide-ranging. Each chapter in this volume is a distillation of the key recent literature in different areas, covering the spectrum of NMR theory and practice, and including theory and computation of nuclear shielding, NMR of soft matter, hyperpolarisation techniques and NMR of living systems. These reports are invaluable both for new researchers wishing to engage with literature for the first time, and for seasoned practitioners, particularly service managers, needing to keep in touch with the ever-expanding ways in which NMR is used.
The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic sy...
Annotation This is a systematic introduction to MTI (moving target indication) system design for use in the fields of earth observation, surveillance and reconnaisance, with particular regard to the suppression of clutter returns. Coverage includes signal processing, clutter models, array processinig theory, adapted linear arrays, non-linear antenna configurations, circular arrays, space-frequency techniques, and clutter suppression jamming conditions. This book is a follow up to the author's successful first book on STAP.
In 2014, the World Health Organization (WHO) listed cancer as the second leading cause of death and highlighted antimicrobial resistance as “a key global health challenge” that may, in a worst case scenario, lead to an annual death toll of 10 million by 2050, which would exceed predicted cancer deaths by 20%. Novel promising therapeutic options to reduce morbidity and mortality of both infectious microbial diseases and cancer are being developed based on antimicrobial peptides (AMPs), i.e., evolutionary proven antibiotics that also possess anti-cancer activities. Intriguingly, AMPs and anti-cancer peptides (ACPs) rely typically on novel mechanisms and cellular targets not used by current...
This book is a collection of Special Issue articles with a multidisciplinary character, linking biology, medicine, and synthetic organic chemistry. The synthesis and full characterization of about 180 novel organic species, both of natural and synthetic origin, often designed with the support of in-silico studies, are set out in the book. In several articles, molecular hybridization approaches have been used as a successful multi-target strategy for the design and development of novel antitumor agents. Rigorous and careful biochemical studies ranging from in-vitro experiments on a plethora of human-cancer derived cell lines to in-vivo and ex-vivo studies allowed the authors to identify the molecular targets and gain useful information on structure–activity relationships (SAR). For this reason, this collection should interest many readers from different scientific fields.
Black Holes in the Era of Gravitational-Wave Astronomy provides a multidisciplinary, up-to-date view of the physics of black holes, along with an exhaustive overview of crucial open questions and recent advancements in the astrophysics of black holes in the wake of incredible advancements made in the last decade. It includes discussions on improvements in theoretical modeling and observational perspectives for black holes of all sizes, along with associated challenges. The book's structure and themes will enable an entwined understanding of black hole physics at all scales, thus avoiding the compartmentalized view that is typical of more specialized manuscripts and reviews.This book is a com...
Environment, Energy and Sustainable Development brings together 242 peer-reviewed papers presented at the 2013 International Conference on Frontiers of Energy and Environment Engineering, held in Xiamen, China, November 28-29, 2013. The main objective of this proceedings set is to take the environment-energydevelopments discussion a step further. Volume 1 of the set is devoted to Energy, power and environmental engineering, and volume 2 to Control, information and applications. Environment, Energy and Sustainable Development is intended to serve as resource material for scientists working on related topics in many disciplines, including environmental science, management science, and energy science and policy analysis, as well as for industry professionals in the wide field of energy and environmental engineering.