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Herbalism, Phytochemistry and Ethnopharmacology
Bridging the gap between the ancient art of herbalism and the emerging sciences of ethnopharmocology and phytopharmacotherapy, this book highlights the major breakthroughs in the history of the field and focuses on future directions in the discovery and application of herb-derived medicines. Implementing the concept of reverse pharmacology, it inte
HPLC for Pharmaceutical Scientists
HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
Practical HPLC Method Development
This revision brings the reader completely up to date on the evolving methods associated with increasingly more complex sample types analyzed using high-performance liquid chromatography, or HPLC. The book also incorporates updated discussions of many of the fundamental components of HPLC systems and practical issues associated with the use of this analytical method. This edition includes new or expanded treatments of sample preparation, computer assisted method development, as well as biochemical samples, and chiral separations.
Generalized Additive Models
This book describes an array of power tools for data analysis that are based on nonparametric regression and smoothing techniques. These methods relax the linear assumption of many standard models and allow analysts to uncover structure in the data that might otherwise have been missed. While McCullagh and Nelder's Generalized Linear Models shows how to extend the usual linear methodology to cover analysis of a range of data types, Generalized Additive Models enhances this methodology even further by incorporating the flexibility of nonparametric regression. Clear prose, exercises in each chapter, and case studies enhance this popular text.
Marine Fisheries Ecology
This topical and exciting textbook describes fisheries exploitation, biology, conservation and management, and reflects many recent and important changes in fisheries science. These include growing concerns about the environmental impacts of fisheries, the role of ecological interactions in determining population dynamics, and the incorporation of uncertainty and precautionary principles into management advice. The book draws upon examples from tropical, temperate and polar environments, and provides readers with a broad understanding of the biological, economic and social aspects of fisheries ecology and the interplay between them. As well as covering 'classical' fisheries science, the book...
Shaping Urban Infrastructures
Cities can only exist because of the highly developed systems which underlie them, ensuring that energy, clean water, etc. are moved efficiently from producer to user, and that waste is removed. The urgent need to make the way that these services are provided more environmentally, socially and economically sustainable means that these systems are in a state of transition; from centralized to decentralized energy; from passive to smart infrastructure; from toll-free to road pricing. Such transitions are widely studied in the context of the influence of service providers, users, and regulators. Until now, however, relatively little attention has been given to the growing role of intermediaries...
Structural Complexity Management
Product design is characterized by a steady increase in complexity. The main focus of this book is a structural approach on complexity management. This means, system structures are considered in order to address the challenge of complexity in all aspects of product design. Structures arise from the complex dependencies of system elements. Thus, the identification of system structures provides access to the understanding of system behavior in practical applications. The book presents a methodology that enables the analysis, control and optimization of complex structures, and the applicability of domain-spanning problems. The methodology allows significant improvements on handling system complexity by creating improved system understanding on the one hand and optimizing product design that is robust for system adaptations on the other hand. Developers can thereby enhance project coordination and improve communication between team members and as a result shorten development time. The practical application of the methodology is described by means of two detailed examples.
Modern Sample Preparation for Chromatography
Modern Sample Preparation for Chromatography, Second Edition explains the principles of sample preparation for chromatographic analysis. A variety of procedures are applied to make real-world samples amenable for chromatographic analysis and to improve results. This book's authors discuss each procedure's advantages, disadvantages and their applicability to different types of samples, along with their fit for different types of chromatographic analysis. The book contains numerous literature references and examples of sample preparation for different matrices and new sections on green approaches in sample preparation, progress in automation of sample preparation, non-conventional solvents for LLE (ionic liquids, deep eutectic mixtures, and others), and more. - Presents numerous techniques applied for sample preparation for chromatographic analysis - Provides an up-to-date source of information regarding the progress made in sample preparation for chromatography - Describes examples for specific types of matrices, providing a guide for choosing the appropriate sample preparation method for a given analysis
Disrupted Cities
Bringing together leading researchers from geography, political science, sociology, public policy and technology studies, Disrupted Cities exposes the politics of well-known disruptions such as devastation of New Orleans in 2005, the global SARS outbreak in 2002-3, and the great power collapse in the North Eastern US in 2003. But the book also excavates the politics of more hidden disruptions: the clogging of city sewers with fat; the day-to-day infrastructural collapses which dominate urban life in much of the global south; the deliberate devastation of urban infrastructure by state militaries; and the ways in which alleged threats of infrastructural disruption have been used to radically r...
