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Horizontal Gene Transfer Mediated Multidrug Resistance: A Global Crisis, 2nd Edition
Throughout history, human life has been seriously threatened by bacterial infectious diseases. After the discovery of antibiotics, humanity thought it had won the fight against infectious bacteria. However, considering the rapid evolution of bacterial multidrug resistance and exhausted pipeline of antibiotics for fighting bacterial infectious diseases, we are approaching the ‘post-antibiotic’ era. Unlike eukaryote, bacteria are proficient in exchanging their genetic materials with others by means of horizontal gene transfer (HGT). As a vehicle for antibiotic resistance gene (ARG), plasmid is self-replicable and transferable in a wide range of host bacteria. Moreover, ways of HGT-mediated...
Antimicrobial Resistance in Bacteria from Livestock and Companion Animals
The global spread of antimicrobial-resistant pathogenic bacteria is a continuing challenge to the health care of humans and domesticated animals. With no new agents on the horizon, it is imperative to use antimicrobial agents wisely to preserve their future efficacy. Led by Editors Stefan Schwarz, Lina Maria Cavaco, and Jianzhong Shen with Frank Møller Aarestrup, an international team of experts in antimicrobial resistance of livestock and companion animals has created this valuable reference for veterinary students and practitioners as well as researchers and decision makers interested in understanding and preventing antimicrobial resistance.
Pseudomonas aeruginosa
This book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen. Pseudomonas aeruginosa is responsible for one out of ten hospital infections. Additionally, this Gram-negative bacterium is accountable for persistent infections in immunocompromised individuals and the leading cause of chronic lung infections in cystic fibrosis patients. This book provides insight on the metabolic versatility of Pseudomonas aeruginosa and its mechanisms for biofilm formation that make this organism highly efficient in causing infections. The book invites the readers to learn mo...
Pseudomonas Methods and Protocols
In Pseudomonas aeruginosa, expert researchers in the field detail many of the methods which are now commonly used to study this fascinating microorganism. Chapters include microbiological methods to high-throughput molecular techniques that have been developed over the last decade. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Pseudomonas aeruginosa aids in the continuing study of new and cutting edge findings.
Jeannette & Jeannot
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Public Administration Reforms in Europe
Based on a survey of more than 6700 top civil servants in 17 European countries, this book explores the impacts of New Public Management (NPM)-style reforms in Europe from a uniquely comparative perspective. It examines and analyses empirical findings regarding the dynamics, major trends and tools of administrative reforms, with special focus on the diversity of top executives’ perceptions about the effects of those reforms.
