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The basis for the hit TV show Mr Selfridge In 1909, the largest department store in London's West End, designed and built from scratch, opened in Oxford Street in a glorious burst of publicity. The mastermind behind the façade was American retail genius Harry Gordon Selfridge: maverick businessman, risk-taker, dandy and one of the greatest showmen the retail world has ever known. His talents were to create the seduction of shopping, and as his success and fame grew, so did his glittering lifestyle: mansions, yachts, gambling, racehorses - and mistresses. From the glamour of Edwardian England, through the turmoil of the Great War and the heady excesses of the 1920s and beyond, Selfridges Department Store was 'a theatre with the curtain going up at 9 o'clock each morning'. Mr Selfridge reveals the captivating story of the rise and fall of the man who revolutionised the way we shop. 'Lively and entertaining' Sunday Telegraph 'Will change your view of shopping forever' Vogue 'Harry Selfridge revolutionised the way we shop ... fascinating' Daily Mail
This book is the compilation of papers presented at the International Symposium on In Vivo Body Composition Studies, held in Houston, Texas, November 10-12, 1992. The purpose of this conference was to report on the state-of-the-art techniques for in vivo body composition measurements and to present the most recent human data on normal body composition and changes during disease. This conference was the third in a series of meetings on body composition studies held in North America, and follows the successful meetings at Brookhaven National Laboratory in 1986, and the one in Toronto in 1989. A large number of excellent research papers were offered for consideration at this Conference which de...
This book provides essential knowledge and informa-tion required to adequately assess useful alternatives from among the lower vertebrates and the invertebrates. This volume highlights unfamiliar and underde-veloped organisms that have the potential to become very satisfactory surrogates for biomedical research. A practical guide aimed at disseminating information to researchers about new models, this work provides compara-tive biomedical studies at many levels of the phyloge-netic ladder.
For this Workshop, the organizers have attempted to invite experts from all known centers which are engaged in neutron beam development for neutron capture therapy. The Workshop was designed around a series of nineteen invited papers which dealt with neutron source design and development and beam characterization and performance. Emphasis was placed on epithermal beams because they offer clinical advantages and are more challenging to implement than thermal beams. Fission reactor sources were the basis for the majority of the papers; however three papers dealt with accelerator neutron sources. An additional three invited papers provided a summary of clinical results of Ncr therapy in Japan b...
This compendium presents some of the major applications of neutron scattering techniques to problems in biology. It is a record of the papers presented at the Neutrons in Biology Conference, the third in an occasional series held to highlight progress in the field and to provide a focus for future direction. The strength ofthe neutron scattering technique remains principally in the manipula tion of scattering density through hydrogen and deuterium atoms. The development ofad vanced detectors, innovative instrument and beamline components, and sophisticated data acquisition systems through the 1970s and early 1980s provided a sound foundation for the technique. With continued development, som...
This book is the compilation of papers presented at the International Symposium on in vivo Body Composition Studies, held at the University of Toronto, Ontario, Canada, June 20 - 23, 1989. The purpose of this conference was to report on advances in techniques for the in vivo measurement of body composition and to present recent data on normal body composition and changes during disease. This conference was the most recent of several meetings on body composition studies, and follows two successful such meetings, one at Brookhaven National Laboratory in 1986, and at Edinburgh in 1988. The large number of excellent research papers and posters presented at these conferences demonstrates the rapi...
This book provides a complete snapshot of various experimental approaches to structure-based and ligand-based drug design and is illustrated with more than 200 images.
First multi-year cumulation covers six years: 1965-70.
Lifestyle, in any part of the world, is associated with the occurrence of major chronic diseases, including coronary heart disease, hypertension, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,60,70,71). The underlying evidence is, in part, based on the evidence of specific diseases in relation to dietary habits in a given geographic region, as well as changes in such disease occurrences in migrant populations from a low risk to a high risk...
Elucidating the structures of biopolymers as they exist in nature has long been a goal of biochemists and biologists. Understanding how these substances interact with themselves, other solutes, and solvents can provide useful insights into many areas of biochemistry, agriculture, food science and medicine. Knowledge of the structure of a protein or complex carbohydrate in its native form provides guidelines for the chemical or genetic modifications often desired to optimize these compounds to specific needs and applications. For example, in the pharmaceutical industry, structure-function relationships involving biopolymers are studied rou tinely as a means to design new drugs and improve the...