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Formal Methods and Software Engineering
This book constitutes the refereed proceedings of the 11th International Conference on Formal Engineering Methods, ICFEM 2009, held in Rio de Janeiro, Brazil, December 2009. The 36 revised full papers together with two invited talks presented were carefully reviewed and selected from 121 submissions. The papers address all current issues in formal methods and their applications in software engineering. They are organized in topical sections on Testing, Protocols, verification, model checking, object-orientation, event-b, compilation, process algebra, refinement, algebraic specifications and real-time systems.
Progress in Nucleic Acid Research and Molecular Biology
Progress in Nucleic Acid Research and Molecular Biology
Translational Toxicology
Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.
The Enzymes
The Enzymes
The Biology of mRNA: Structure and Function
The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting on the mRNAs, leading to a properly folded complex. This book shows how new technologies have led to a better understanding of these processes and their connected diseases.The book is written for scientists in fundamental and applied biomedical research working on different aspects of gene regulation. It is also targeted to an audience that is not implicated in these fields directly, but wants to gain a better understanding of mRNA biology.
Celebrating 5 Years of Avian Physiology in Frontiers in Physiology
The avian physiology section is now five years old. This special e-book is to commemorate this event. For this highlights issue celebrating the first five years of the Avian Physiology section, it was decided to focus on the top papers/reviews published. Table 1 lists the top fifteen papers/reviews based on either views or down-loads as a pdf. There is some agreement between the two lists. What is compelling is that of the top papers, all except one encompasses research conducted in domesticated birds, predominantly with chickens with one focused on turkeys. It is perhaps not unexpected that research on chickens dominates the top papers because of the following: - Chickens are commercially i...
Progress in Medicinal Chemistry
There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.
Advances in Pharmacology
Advances in Pharmacology
