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Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
EDITOR-IN-CHIEF: Clifford J. Rosen, M.D., Maine Medical Center Research Institute, Scarborough, Maine SENIOR ASSOCIATE EDITORS: Juliet E. Compston, M.D., FRCP, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom Jane B. Lian, Ph.D., University of Massachusetts Medical School, Worcester, Massachusetts This comprehensive yet concise handbook is an indispensable reference for the many clinicians who see patients with disorders of bone formation, metabolic bone diseases, or disorders of stone formation. It is also a crucial tool for researchers, students, and all other professionals working in the bone field. In a format designed for quick reference, it provides comple...
Principles of Bone Biology
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Comprehensive Coordination Chemistry II
Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.
Handbook of African Philosophy
This Handbook provides in one volume rich, comprehensive and rigorous coverage of specific subject areas and thematic concerns in the ever-evolving academic discipline of African philosophy. This Handbook is unique in its focus on central and emerging areas within African philosophy such as Afro-communitarian philosophy, ethics, epistemology, social and political philosophy, existentialism, philosophy of religion, gender philosophy, philosophy of education, phenomenology, transhumanism, African philosophy futures, and philosophy of the non-human. The thirty-two chapters in this Handbook explore the rich textual and non-textual forms of philosophical knowledge in Africa and adequately represent the broad and diverse scope of African philosophy, showing the richness and depth of the philosophical tradition. This reference work is indispensable to students and researchers in African philosophy, comparative philosophy and world philosophies.
Computational Neuroscience
This volume looks at the latest advancements in imaging neuroscience methods using magnetic resonance imaging (MRI) and electroencephalography (EEG) to study the healthy and diseased brain. The chapters in this book are organized into five parts. Parts One and Two cover an introduction to this field and the latest use of molecular models. Part Three explores neurophysiological methods for assessment, such as quantitative EEG and event-related potentials. Part Four discusses the advances and innovations made in computational anatomy, and Part Five addresses the challenges faced by researchers prior to the computational neuroscience to find wider translational applications in the field of psychiatry and mental health. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Computational Neuroscience is a valuable tool for researchers in the psychiatry and mental health fields who want to learn more about ways to incorporate computational approaches into utility and validity of clinical methods.
Osteoporosis and Bone Densitometry Measurements
Osteoporosis is a serious problem worldwide, and its significance is continuing to increase as the world population grows and ages. Osteoporosis and Bone Densitometry Measurements provides a comprehensive review of the latest research on this potentially devastating condition. The book encompasses prevention, diagnosis, and therapy, providing state of the art information on each aspect. A wide range of topics are discussed, including differentiation between acute and chronic, benign and malignant vertebral fractures; the value of the WHO FRAX tool in patient evaluation; the roles of dual-energy X-ray absorptiometry, quantitative computed tomography, quantitative ultrasound, and high-resolution imaging; and the use of kyphoplasty and vertebroplasty to treat vertebral compression fractures. All chapters are written by acknowledged experts in the field.
Proximity Labeling
This book provides detailed protocols and untold tips and tricks regarding the most well-known examples of proximity labeling methods, in which the protein of interest is genetically fused to or labeled with an enzyme that can generate short-lived reactive species to non-specifically label molecules within a certain radius of up to twenty nanometers. Beginning with peroxidase-based proximity labeling methods, the volume continues with BioID, proximity labeling methods that describe the proximity ligation assay to detect RNA-DNA interactions, UV cross-linking to demonstrate RNA-protein interactions, and how chemical and enzymatic reactivities can be improved upon DNA-DNA and protein-protein i...
