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In just 10 years, Marianne Breslauers career as a photographer had marked her out as an ambitious photojournalist of the late Weimar Republic, before emigration and the outbreak of war brought this auspicious beginning to an abrupt halt. Educated from 1927 to 1929 at the renowned Lette-Haus in Berlin, Marianne Breslauer went next to Paris. Her first posting was with Man Ray, who told the 20-year-old that she could do everything already and warmly invited her to make use of his studio. She gladly took up the offer, yet her intrinsic domain remained the the street: the quays of the Seine, the Jardin du Luxembourg, the street performers on the Rue dOrléans. These photos attracted the attention...
DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molecular interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of Advances in DNA Sequence Specific Agents. As was the case for Volume 1, Part A also covers methodology, but in Volume 2 we include calorimetric titrations, molecular modeling, X-ray crystallographic and NMR structural studies, and transcriptional assays. Part B also follows the same format as Volume 1 and describes the sequence specificities and covalent and noncovalent interactions of small ligands with DNA.This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition.
The applications and interest in thermal analysis and calorimetry have grown enormously during the last half of the 20th century. These techniques have become indispensable in the study of processes such as catalysis, hazards evaluation etc., and in measuring important physical properties quickly, conveniently and with markedly improved accuracy. Consequently, thermal analysis and calorimetry have grown in stature and more scientists and engineers have become at least part-time, practitioners. People new to the field therefore need a source of information describing the basic principles and current state of the art. The last volume of this 4 volume handbook, devoted to many aspects of biological thermal analysis and calorimetry, completes a comprehensive review of this important area. All chapters have been prepared by recognized experts in their respective fields. The approach taken is "how and what to do and when to do it". The complete work is a valuable addition to the already existing literature.
Advances in Biophysical Chemistry, Volume 5, provides reviews of important topics in physical and structural biochemistry. The volume begins with a review of the chemical reactivity of DNA and its relationship to the dynamic nature of DNA conformation and its dependence on base sequence. The underlying chemistry has become extremely important to many researchers who use a host of chemical "footprinting" techniques to study biologically relevant complexes of DNA. This is followed by separate chapters that cover an innovative application of fluorescence energy transfer to investigate the dynamics of complex glycopeptides; the NMR of cations which bind to DNA, providing a picture of DNA conformation and dynamics which is complementary to that provided by 1H NMR spectroscopy; the use of NMR to study electron transfer reactions between cytochrome c peroxidase and cytochrome c; methods for analysis of data on O2 binding by hemoglobin; and experimental methods for obtaining data on protein association.
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This book examines how some modern and contemporary Jewish thinkers and writers have imagined a Judaism without the boundaries and restrictions that go by the name of "religion." The book offers scholarly insights into some Jewish thinkers-notably Martin Buber and Eugene Borowitz, some Jewish writers-in particular the poet Hayyim Nahman Bialik and the Yiddish author I.L. Peretz. The study also introduces more contemporary thinkers and writers such as the postmodernist Jacques Derrida, the contemporary Israeli novelist David Grossman, and the young Israeli poet Ilan Sheinfeld. While of scholarly interest, the ten chapter work has more general appeal as a way of conceiving Jewish living outsid...