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The axon, interposed between the cell body and the synaptic terminals in most neurons, plays a crucial role in connecting neurons and acting as a conduit for the transmission of information between them. This book provides a comprehensive and up-to-date compendium that brings together chapterson the structure, function, and pathophysiology of axons in both the PNS and CNS. Carefully written, well-illustrated with superb illustrations, and generously referenced, the 33 chapters and introduction have been authored by 49 world-renowned authorities. Recent advances in the molecularneurobiology of axons are carefully reviewed, and new areas, such as the molecular biology of ion channels and myelination, the role of calcium in pathophysiology and regeneration, cell adhesion molecules and their roles in axo-glial interactions and axonal guidance, and optical recording methods,are highlighted. This book will provide an essential reference for neuroscientists as well as clinicians such as neurologists, neurosurgeons, and clinical electrophysiologists interested in axons.
"This book provides a much needed understanding of how management can deal with the impact of politics and culture on the overall utilization of information technology within an organization"--Provided by publisher.
As organizations are competing globally in this new millennium, the effective deployment and exploitation of IT will create the difference between those that are successful and those that are not. What lessons are there to be learned from organizations that run global IT operations and deploy IT in support of their global business operations? Cases on Global IT Applications and Management: Successes and Pitfalls brings together original cases that report on these aspects of global IT applications and management and benefits educators, researchers and practitioners alike.
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Understanding how the brain works is probably the greatest scientific and intellectual challenge of our generation. The cerebral cortex is the instrument by which we carry the most complex mental functions. Fortunately, there exists an immense body of knowledge concerning both cortical structure and the properties of single neurons in the cortex. With the advent of the supercomputer, there has been increased interest in neural network modeling. What is needed is a new approach to an understanding of the mammalian cerebral cortex that will provide a link between the physiological description and the computer model. This book meets that need by combining anatomy, physiology, and modeling to achieve a quantitative description of cortical function. The material is presented didactically, starting with descriptive anatomy and comprehensively examining all aspects of modeling. The book gradually leads the reader from the macroscopic cortical anatomy and standard electrophysiological properties of single neurons to neural network models and synfire chains. The most modern trends in neural network modeling are explored.
Axons are neuronal output elements and are responsible for the transfer and processing of signals from one neuron to another, even over very large distances. For a given neuronal cell type, axons are unique and display very heterogeneous patterns with respect to shape, length and target structure. Axons are the usually long process of a nerve fiber that generally conducts impulses away from the body of the nerve cell. This book is intended to summarize recent findings covering morphological, physiological, developmental, computational and pathophysiological aspects of axons. It attempts to cover new findings concerning axonal structure and functions together with their implications for signal transduction, processes implicated in the formation of axonal arbors and the transport of subcellular elements to their targets, and finally how a dysfunction in one or several of these steps could lead to axonal degeneration and ultimately to neurodegenerative diseases.
The newly revised, comprehensive, four-color Atlas of Clinical Neurology is extensively updated with reference to current literature. The new third edition organizes the highest-quality images from the field of clinical neurology, including clinical syndromes, for neurologists and clinicians. The atlas highlights the enormous strides being made in the biologic understanding of neurologic disease, covering developmental and genetic diseases, neuroendocrine disorders, critical care neurology, cerebrovascular disease, dementias, behavioral neurology, neuro-oncology, movement disorders, epilepsy, neuromuscular diseases, infectious diseases, neuroimmunology, neurotoxic disorders, and headache. This indispensable collection contains over 1300 images including algorithms, tables, charts, and schematic drawings.
Praise for the previous edition:This work has great visual appeal and superb images...a superior text that will undoubtedly withstand the test of time.--GastroenterologyWritten and edited by internationally renowned specialists, the second edition of Gastroenterological Endoscopy covers the entire spectrum of diagnostic and therapeutic procedures for the upper and lower GI tract and provides an up-to-date overview of GI disorders. The book opens with a section on the development and technology of endoscopy, followed by an expanded section on issues related to patient care, such as informed consent, sedation, and special clinical conditions. The discussion of techniques for the diagnosis of G...
Hours of great reading await, with adventure tales culled from the pulp magazines of the early 20th century by some of the most renowned pulp authors, including Robert E. Howard (creator of Conan the Barbarian), Harold Lamb, William Hope Hodgson, Dorothy Quick, E. Hoffmann Price, and many more! More than 500 pages of fiction! (Search for ?megapack? to find all the other great titles in this series.) Included in this volume: THE BLACK ADDER, by Dorothy Quick EVERY MAN A KING, by E. Hoffmann Price SON OF THE WHITE WOLF, by Robert E. Howard PEARL HUNGER, by Albert Richard Wetjen A MEAL FOR THE DEVIL, by K. Christopher Barr JACK GREY, SECOND MATE, by William Hope Hodgson SAID AFZEL’S ELEPHANT,...
Currently, the modelling and control of mechatronic and robotic systems is an open and challenging field of investigation in both industry and academia. The book encompasses the kinematic and dynamic modelling, analysis, design, and control of mechatronic and robotic systems, with the scope of improving their performance, as well as simulating and testing novel devices and control architectures. A broad range of disciplines and topics are included, such as robotic manipulation, mobile systems, cable-driven robots, wearable and rehabilitation devices, variable stiffness safety-oriented mechanisms, optimization of robot performance, and energy-saving systems.