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Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
Proceedings of a conference sponsored by the American Association of Pharmaceutical Scientists, the U.S. Food and Drug Administration, and the American Society for Clinical Pharmacology and Therapeutics, held in Arlington, Virginia, April 24-26, 1991
Analytical Profiles of Drug Substances and Excipients
Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the American Association of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The scope of the series has recently been expanded to include profiles of excipient materials.
Nanosources and Manipulation of Atoms Under High Fields and Temperatures: Applications
This volume contains the proceedings of the NATO-Advanced Research Workshop (ARW) "Manipulation of atoms under high fields and temperatures: Applications", sponsored by the NATO Scientific Affairs Division, Special Programme on Nanoscale Science. This ARW took place in Summer '92, in the pleasant surroundings of the Hotel des Thermes at Charbonnieres les Bains -Lyon, France. Gathering some fifty experts from different fields, the ARW provided an opportunity to review the basic principles and to highlight the progress made during the last few years on the nanosources and the interactions between atomic-scale probes and samples. The motivation is to use the novel properties attached to the ato...
Annual Reviews of Computational Physics IV
Quantum phenomena and methods are the core of this volume in our series which publishes rapidly reviews of topics in computational physics. In addition, we look at phase transitions in Ising lattices, in continuum fluids, polymer solutions, and end with biological ageing. As before, papers were submitted by e-mail, and these files were used directly to produce the book, for increased speed and reliability. Contents:Preface (D Stauffer)Simulations of Magnetic Fluids (M J P Nijmeijer & J J Weis)Critical Phenomena in Simple and Complex Fluids (N B Wilding)Quantum Monte Carlo on a Lattice: The World Line Algorithm (G G Batrouni)Computer Simulation of Quantum Phenomena in Nanoscale Devices (H De ...
Lake Kinneret
This condensed volume summarizes updated knowledge on the warm-monomictic subtropical Lake Kinneret, including its geophysical setting, the dynamics of physical, chemical and biological processes and the major natural and anthropogenic factors that affect this unique aquatic ecosystem. This work expands on a previous monograph on Lake Kinneret published in 1978 and capitalizes on the outcome of more than 40 years of research and monitoring activities. These were intensively integrated with lake management aimed at sustainable use for supply of drinking water, tourism, recreation and fishery. The book chapters are aimed at the limnological community, aquatic ecologists, managers of aquatic ec...
Systemic Lupus Erythematosus
This book provides a comprehensive overview of the basic and clinical sciences of Systemic Lupus Erythematosus. It is suitable for basic scientists looking for detailed coverage of their areas of interest. It describes how advances in molecular biology have increased our understanding of this disease. It is a valuable clinical resource for practicing clinicians from different disciplines including rheumatologists, rheumatology fellows and residents. This book provides convenient access to information you need about cytokines, genetics, Fas pathway, toll like receptors and atherogenesis in SLE. Animal models have been reviewed as well. How to avoid delay in SLE diagnosis and management, in addition to various clinical manifestations including pregnancy and SLE have all been explained thoroughly in this book.
Scanning Tunneling Microscopy and Related Methods
Proceedings of the NATO Advanced Study Institute on Basic Concepts and Applications of Scanning Tunneling Microscopy, Erice, Italy, April 17-29, 1989
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
Volume 43 of «Progress in Drug Research» contains five reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with high cholesterol blood levels and other dyslipidemias; search of ideal antihypertensive drugs; the natural PQlyamines and the immune system; biologically active quinazolones and with production and action of interferons. In the 35 years the PDR has existed, the Editor has enjoyed the valuable help and advice of many colleagues. Readers, the authors of the reviews, and last but not least, the reviewers have all contributed greatly to the success of this series. Although the comments recei...
Recurrent Pregnancy Loss
Recurrent pregnancy loss presents a vexing clinical problem primarily for medical professionals treating patients in reproductive medicine and in maternal-fetal medicine. However, with its numerous causes and various suggested treatment options, the problem is more multidisciplinary in nature, involving gynecology, genetics, endocrinology, immunology, pediatrics, and internal medicine. Exploring basic science and clinical applications, the second edition of the bestselling text Recurrent Pregnancy Loss: Causes, Controversies, and Treatment provides an authoritative and comprehensive update on advances in the understanding and management of this troubling phenomenon. The book covers basic sci...
