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Behavioral Neurobiology of Psychedelic Drugs
This volume brings together the latest basic and clinical research examining the effects and underlying mechanisms of psychedelic drugs. Examples of drugs within this group include LSD, psilocybin, and mescaline. Despite their structural differences, these compounds produce remarkably similar experiences in humans and share a common mechanism of action. Commonalities among the substances in this family are addressed both at the clinical and phenomenological level and at the basic neurobiological mechanism level. To the extent possible, contributions relate the clinical and preclinical findings to one another across species. The volume addresses both the risks associated with the use of these drugs and the potential medical benefits that might be associated with these and related compounds.
The Pharmacology of LSD
LSD has a controversial and extraordinary reputation, due to the special effects it can induce on human consciousness.This book is the first ever comprehensive review of the psychological and pharmacological effects of LSD. It draws on data from more than 3000 experimental and clinical studies.
Medical Research Ethics: Challenges in the 21st Century
This book provides a current review of Medical Research Ethics on a global basis. The book contains chapters that are historically and philosophically reflective and aimed to promote a discussion about controversial and foundational aspects in the field. An elaborate group of chapters concentrates on key areas of medical research where there are core ethical issues that arise both in theory and practice: genetics, neuroscience, surgery, palliative care, diagnostics, risk and prediction, security, pandemic threats, finances, technology, and public policy.This book is suitable for use from the most basic introductory courses to the highest levels of expertise in multidisciplinary contexts. The insights and research by this group of top scholars in the field of bioethics is an indispensable read for medical students in bioethics seminars and courses as well as for philosophy of bioethics classes in departments of philosophy, nursing faculties, law schools where bioethics is linked to medical law, experts in comparative law and public health, international human rights, and is equally useful for policy planning in pharmaceutical companies.
An Introduction to the Study of Mysticism
2022 CHOICE Outstanding Academic Title The purpose of this book is to fill a gap in contemporary mystical studies: an overview of the basic ways to approach mystical experiences and mysticism. It discusses the problem of definitions of “mystical experiences” and “mysticism” and advances characterizations of “mystical experiences” in terms of certain altered states of consciousness and “mysticism” in terms of encompassing ways of life centered on such experiences and states. Types of mystical experiences, enlightened states, paths, and doctrines are discussed, as is the relation of mystical experiences and mysticism to religions and cultures. The approaches of constructivism, ...
Handbook of the Behavioral Neurobiology of Serotonin
Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful d...
Making Sense of Marshall Ledbetter
Armed with an empty whiskey bottle and wearing a tie-dyed Jimi Hendrix T-shirt, Florida State University dropout Marshall Ledbetter broke into the Florida State Capitol early one morning in June 1991. He occupied the Sergeant of Arms suite, demanding an extra-large Gumby’s pizza and 666 donuts for the cops waiting outside. He hoped to garner media attention for his protest of poverty, homelessness, and cuts to higher education. After an eight hour standoff, Ledbetter was betrayed by the very media he had counted on to tell his story; his demands were not broadcast on CNN as he had been promised but streamed into the office on closed-circuit TV. Although he left the building peacefully, the...
A Different Medicine
In 'A Different Medicine', Joseph Calabrese presents a case study that challenges many deeply ingrained cultural assumptions and attempts to mediate a centuries-old clash of cultural paradigms. The book explores a controversial Native American ritual and healthcare practice: ceremonial consumption of the psychedelic Peyote cactus in the context of a postcolonial healing movement called the Native American Church. Calabrese argues against the War on Drugs and the Supreme Court decision that jeopardized the right of Native Americans to use this medicine. He urges us to recognize the multiplicity of the normal and the therapeutic.
Biological Research on Addiction
Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual's susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of...
The Rise and Fall of Animal Experimentation
Every year, hundreds of millions of animals are used in the service of biomedical research, despite the risk of extreme cruelty to these animal subjects. The expansion of the pharmaceutical industry and university research funding rapidly normalized its practice. What exactly are these experiments supposed to achieve from the scientific point of view and how effective are they? Working scientists answer these questions by saying that their research is absolutely necessary if we are to develop new therapies for human diseases. But is this really the case? Written by a scientist with over 40 years of laboratory experience, The Rise and Fall of Animal Experimentation critically examines this as...
The Palgrave Handbook of Philosophy and Psychoactive Drug Use
Zusammenfassung: In this Handbook, philosophers from around the world address the metaphysics, epistemology, and value of psychoactive (mind-altering) drug use. In so doing, they attempt to answer questions such as: What does the fact of drug-induced mind-altering experiences tell us about natures of the mind, free will, and God? What does it tell us about what, and how, we can know? Are drug-induced mind-altering experiences valuable, morally, aesthetically, or otherwise? Is the acquisition of drug-induced mind-altering experiences ever immoral? Should the acquisition of drug-induced mind-altering experiences ever be legally prohibited? The Handbook gives an overview of the current research, and sets the stage for future directions in philosophical thought relating to psychoactive drug use. Rob Lovering is Professor of Philosophy at the City University of New York - College of Staten Island, USA. His previous books include God and Evidence: Problems for Theistic Philosophers (2013), A Moral Defense of Recreational Drug Use (2015), and A Moral Defense of Prostitution (2021)
