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HCV: The Journey from Discovery to a Cure
Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide. It is also one of the major causes of liver cancer and liver transplants. The elucidation of the HCV genome, and the development of a whole cell system to study the virus spurred the search for novel direct acting antiviral drugs to cure this disease. This global effort culminated in the development of direct acting antiviral drugs that led to cure rates approaching 100% in all patient populations after only 8-12 weeks of therapy. These efforts resulted in one of the greatest achievements in public health and provides the potential for eliminating HCV as a major...
The United Nations and Sustainable Development Goals
The book is a collection of analyses on country-specific and universal efforts, programmes and projects from Africa and beyond, aimed at realising the Sustainable Development Goals (SDGs). Specifically, the chapters focus on the achievements and challenges that can potentially aid countries of the world and the United Nations in achieving the 17 SDGs. The chapters focus more on the challenges, prospects and concrete steps taken in the Global South towards the attainment of these goals.
HIV and AIDS
The continuing AIDS pandemic reminds us that despite the unrelenting quest for knowledge since the early 1980s, we have much to learn about HIV and AIDS. This terrible syndrome represents one of the greatest challenges for science and medicine. The purpose of this book is to aid clinicians, provide a source of inspiration for researchers, and serve as a guide for graduate students in their continued search for a cure of HIV. The first part of this book, "From the laboratory to the clinic," and the second part, "From the clinic to the patients," represent the unique but intertwined mission of this work: to provide basic and clinical knowledge on HIV/AIDS.
Norovirus
This book addresses the molecular biology of noroviruses (NoVs), pathogenesis, viral diversity and its impact on selective pressure, host susceptibility and outbreaks, clinical diagnosis, and the latest advances in the management and treatment of disease caused by NoVs. It offers a detailed analysis of our current understanding of the innate and the adaptive immune responses stimulated by NoVs, and discusses the complexity of the ongoing vaccine development and the urgent need for specific immune correlates of protection to advance the field. This is the first book on noroviruses. Written by leading specialists, it is essential reading for virologists and immunologists.
Global Food Politics and Approaches to Sustainable Consumption: Emerging Research and Opportunities
Food production and consumption processes are largely governed via control mechanisms that affect food accessibility and environmental efficiency. Food resource marginalization, inequality, and deleterious consumption urgently require new governance and developmental systems that will provide food security and create consumption patterns that protect the natural environment and food resources. Global Food Politics and Approaches to Sustainable Consumption: Emerging Research and Opportunities is an essential reference source that discusses the challenges and solutions of food security and consumption control. Food politics can be linked to persistent challenges of inequitable access, food resource inefficiency, and control and consumption, which form part of the local development realities that can address global sustainable development. While highlighting topics such as rural agriculture, capitalism, and food chain management, this publication is ideally designed for policymakers, sustainable developers, politicians, ecologists, environmentalists, corporate executives, farmers, and academicians seeking current research on the policies and modalities of food efficiency and equality.
Postcolonial Linguistic Voices
This volume investigates sociolinguistic discourses, identity choices and their representations in postcolonial national and social life, and traces them to the impact of colonial contact. The chapters stitch together current voices and identities emerging within both ex-colonized and ex-colonizer communities as each copes with the social, lingual, cultural, and religious mixes triggered by colonialism. These mixes, reflected in the five thematic parts of the book - 'postcolonial identities', 'nationhood discourses', 'translating the postcolonial', 'living the postcolonial', and 'colonizing the colonizer' - call for deeper investigations of postcolonial communities using emic approaches.
Proceedings of the Unima International Conference on Social Sciences and Humanities (UNICSSH 2022)
This is an open access book. The Unima International Conference on Social Sciences and Humanity (UNICSSH) 2022 was conducted on October, 11th – 13th 2022, at The Grand Kawanua International City, Manado, North Sulawesi, Indonesia. In 2022, Universitas Negeri Manado will host the Indonesian National Education Convention (KONASPI) X. Konaspi is a routine activity of the PPTKN which is held once every four years. The fourth industrial revolution (4.0) is marked by technological advances and supported by artificial intelligence that creates opportunities and challenges for the education system. University and vocational school graduates are facing a world transformed by technology which in tur...
Global Challenges for the Environment and Climate Change
Rampant deforestation, rising carbon emissions, and more unprecedented threats are creating chaos and turmoil for the environment. The delicate balance between nature and humanity seems to waver on the brink of collapse. Climate change exacerbates standard occurrences of natural disasters, and endangers countless species. Amid these daunting challenges, the need for comprehensive research and actionable solutions has never been greater. Global Challenges for the Environment and Climate Change draws upon the latest research and empirical findings, and offers a roadmap for navigating the complexities of our interconnected world. Exploring topics such as climate change, sustainable consumption, and global governance equips readers with the knowledge and insights needed to effect meaningful change.
