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This volume is an integrated overview and synthesis of available data relating to the Quaternary evolution of the River Trent. It provides detailed descriptions of the Pleistocene sedimentary records from the Trent, its tributaries and related drainage systems - a sedimentary record that spans a period of approximately half a million years - and the biostratigraphical and archaeological material preserved therein. Significant new data are presented from recently discovered sites of geological and archaeological importance, including previously unrecognised fluvial deposits, as well as novel analyses, such as mathematical modelling of fluvial incision as recorded by the river terrace deposits...
1:Introduction 2:Key issues in taxing profit 3:The current international tax system 4:Fundamental reform options 5:Basic choices in considering reform 6:Residual profit allocation by income 7:Destination-based cash flow taxation.
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The biopharmaceutical market has come along way since 1982 when the first biopharmaceutical product, recombinant human insulin, was launched. Over 120 such products are currently being marketed around the world including nine blockbuster drugs. The global market for biopharmaceuticals, which is currently valued at US$41 billion, has been growing at an impressive compound annual growth rate of 21% over the previous five years. With over one third of all pipe-line products in active development are biopharmaceuticals, this segment is set to continue outperforming the total pharmaceutical market and could easily reach US$100 billion by the end of this decade.