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The Sticky Synapse
The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive mol...
The Biology of Hagfishes
The hagfishes comprise a uniform group of some 60 species inhabiting the cool or deep parts of the oceans of both hemispheres. They are considered the most primitive representatives of the group of craniate chordates, which - apart from the hagfishes that show no traces of verte brae -includes all vertebrate animals. Consequently the hagfishes have played and still playa central role in discussions concerning the evolution of the vertebrates. Although most of the focus on hagfishes may be the result of their being primitive, it should not be forgotten that, at the same time, they are specialized animals with a unique way of life that is interesting in its own right. It is now more than 30 years since a comprehensive treatise on hagfishes was published. The Biology of Myxine, edited by Alf Brodal and Ragnar Fange (Universitetsforlaget, Oslo, 1963), provided a wealth of information on the biology of hagfishes, and over the years remained a major source of information and inspiration to students of hagfishes.
The Fly Neuromuscular Junction: Structure and Function
The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful tool to understand the normal function of these genes. This book reviews outstanding work by recognized leader...
Encyclopedic Reference of Cancer
This comprehensive encyclopedic reference provides rapid and focused information about topics of cancer research for the clinical and basic scientist, students and informed laymen. It will be readily accessible, both electronically and in print, such that it will be of value to both the scientific community and the public.
Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition
Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Managerial Capitalism, Ethics, Secrets and the Business School
By interlacing the threads of managerial development through the 19th, 20th, and early 21st centuries, from capitalist managerialism to the emergence of management consultancy and management education, with particular focus on the American context, this book sheds light on the opportunities, challenges, and pitfalls facing the modern manager today. Especially relevant to aspiring managers seeking to learn more about business, serious questions are asked about management education and its provision. Providing an exposé on (and denunciation of) managerial fallacies, management failures, academic treachery, and greed, the author directly addresses the need for professional managers, to cope with the challenges on this planet to come. With a deep historical knowledge, breadth of vision and equally intellectually daring insight, the author offers the keys not only to an understanding of how we have reached our current position, but more importantly, how we might progress from here. This book sets the tone and heralds the need for real, practical, decisive change, leading to a more ethical, sustainable future.
China Rising
This refreshing analysis approaches the issue of China's potential power on the international stage within the context of its relationships with other international actors, examining the effect such a large power will have on world-wide decisions.
The Toho Studios Story
Since its inception in 1933, Toho Co., Ltd., Japan's most famous movie production company and distributor, has produced and/or distributed some of the most notable films ever to come out of Asia, including Seven Samurai, Godzilla, When a Woman Ascends the Stairs, Kwaidan, Woman in the Dunes, Ran, Shall We Dance?, Ringu, and Spirited Away. While the western world often defines Toho by its iconic classics, which include the Godzilla franchise and many of the greatest films of the legendary director Akira Kurosawa and actor Toshiro Mifune, these pictures represent but a tiny fraction of Toho's rich history. The Toho Studios Story: A History and Complete Filmography provides a complete picture o...
