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Preimplantation Genetics
Yury Verlinskyand Anver Kuliev Reproductive Genetics Institute, Illinois Masonic Medical Center, 836 W. Wellington chicago, IL 60657 Although introduction of a first trimester prenatal diagnosis by chorionic viIIus sampling (CVS) has considerably improved the possibility for prevention of genetic diseases, it requires a selective abortion in case of an affected fetus. Following the direction of an earlier prenatal diagnosis and to avoid the need for abortion, preimplantation genetic diagnosis has been initiated based on polar body removal and pre-embryo biopsy. The First International symposium on Preimplantation Genetics, Chicago, September 17-19, 1990, was organized to explore these import...
Born and Made
Are new reproductive and genetic technologies racing ahead of a society that is unable to establish limits to their use? Have the "new genetics" outpaced our ability to control their future applications? This book examines the case of preimplantation genetic diagnosis (PGD), the procedure used to prevent serious genetic disease by embryo selection, and the so-called "designer baby" method. Using detailed empirical evidence, the authors show that far from being a runaway technology, the regulation of PGD over the past fifteen years provides an example of precaution and restraint, as well as continual adaptation to changing social circumstances. Through interviews, media and policy analysis, a...
Preimplantation Genetic Diagnosis
Preimplantation Genetic Diagnosis (PGD) is the detection and screening of genetic abnormality in gametes prior to fertilisation and embryos fertilised in vitro prior to implantation. This exciting new text provides an introduction and overview of the principles of PGD. An exciting fusion of prenatal diagnosis (PD) with in vitro fertilisation (IVF), this book is will appeal to both the prenatal diagnosis community, of clinical geneticists and foetal medicine specialists within obstetrics and gynaecology, and the IVF community within reproductive medicine. It is also an essential introduction to PD, clinical genetics and IVF for non-specialists. A concise introduction to the field of PGD Detailed explanations of the techniques and procedures used The law and ethical implications of PGD Future uses of PGD
Textbook of Assisted Reproductive Technologies
Textbook of Assisted Reproductive Technologies is a truly comprehensive manual for the whole team at the IVF clinic. Information is presented in a highly visual manner, allowing both methods and protocols to be consulted easily. The text provides clinical and scientific teams with the A to Zs of setting up an embryology laboratory, gives research fellows insight into technical developments, and supplies seasoned professionals with a review of the latest techniques and advances. New to the Third Edition: fully revised and expanded chapters, with new information on: single embryo transfer artificial gametes pharmacogenetics
Making Multiple Babies
Human beings have been producing more twins, triplets, and quadruplets than ever before, due to the expansion of medically assisted conception. This book analyzes the anticipatory regimes of making multiple babies. With archival documents, participant observation, in-depth interviews, and registry data, this book traces the global and local governance of the assisted reproductive technologies (ARTs) used to tackle multiple pregnancy since the 1970s, highlighting the early promotion of single embryo transfer in Belgium and Japan and the making of the world’s most lenient guidelines in Taiwan.
Encyclopedia of Stem Cell Research
"Provides an understanding of the basic concepts in stem cell biology and addresses the politics, ethics, and challenges currently facing the field"--From publisher description.
Law, Policy and Reproductive Autonomy
Reproductive choices are at once the most private and intimate decisions we make in our lives and undeniably also among the most public. Reproductive decision making takes place in a web of overlapping concerns - political and ideological, socio-economic, health and health care - all of which engage the public and involve strongly held opinions and attitudes about appropriate conduct on the part of individuals and the state. Law, Policy and Reproductive Autonomy examines the idea of reproductive autonomy, noting that in attempting to look closely at the contours of the concept, we begin to see some uncertainty about its meaning and legal implications - about how to understand reproductive au...
Biotechnology: Scientific Advancement Versus Public Safety
In this book, Dr Quintyn considers whether genetic engineering will exacerbate social injustices and/or lead to public safety issues. As designer babies mature, will they feel a sense of superiority or pass on mutations that negatively affect future generations? Should we ignore the risk of zoonotic (animal) diseases because they offer potential benefits for reducing organ shortages? Scientific advancement, if not guided responsibly and with public input, can be detrimental to public safety.This book is unique as it encompasses many biotechnologies within the definition of biotechnology. It gives a balanced view of biotechnology: its promise as evidenced in repairing mutations (i.e., genetic...
Biophysical Methods for Diagnosing Human Tissue Anomalies
Medical diagnosis of tissue anomalies, particularly cancer, is often limited by the constraints of current imaging technologies. This book introduces two approaches to address this issue: the imaging and the non-imaging methods. In the imaging category, the book unveils a pioneering technique based on radio tomosynthesis. Initially proven effective in detecting breast anomalies, this imaging method is now under evaluation for its potential in identifying brain anomalies. For non-imaging diagnostics, it delves into Fourier-transform infrared spectroscopy (FTIR), a technique known for its speed and reliability. The book demonstrates its successful application in diagnosing a range of cancers, including oral, uterine, ovarian, gastrointestinal, colorectal, and skin cancers. Furthermore, it explores its utility in predicting embryo quality and assessing pressure injuries. To augment these methods, the book employs machine learning algorithms, evaluating their efficacy in creating discriminative models for tissue anomalies.
40 Years After In Vitro Fertilisation
As a capstone of the commemorations of the 40th anniversary of the birth of the first baby conceived by in vitro fertilization (IVF), in 1978, this collection gathers the principal actors of the history of IVF, and summarizes the main achievements, current state, and future prospects of this technique. The contributions here cover, in a historical perspective, all major aspects of IVF, including its indications and techniques, the basic concepts of ovarian stimulation, the cryopreservation of embryos and oocytes, oocyte in vitro maturation, and technical aspects of oocyte retrieval and embryo transfer, among many other topics. The volume not only provides topical information to health professionals, but is written in such a way that it is understandable to the lay public who may read it as a passionate story of the evolution of techniques intimately related to the origin of human life.
