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In the past decade it has become increasingly clear that psoriatic disease, both of the skin and joints, can be a significant diagnostic and therapeutic challenge for the physician and a debilitating illness for the patient. At the same time, advances in genetics and immunology have increased our understanding of the pathophysiology of psoriasis and psoriatic arthritis. This text contains a comprehensive discussion by an international group of experts in psoriatic disease of the pathomechanisms, genetics, diagnosis, and treatment of psoriasis and psoriatic arthritis. The information is presented in parallel in order to emphasize the similarities and differences between these two diseases that so commonly occur together. We believe that this approach will make this text an important resource for all practitioners who treat patients with psoriasis and psoriatic arthritis.
This reference presents research and clinical developments in the field, presenting comprehensive, problem-focused approaches to psychodermatology. It offers a panoramic perspective of worldwide research efforts to improve the understanding and treatment of the psychodermatological patient.
Which Springbok match saw the least number of spectators ever attending a test match? Who was the unofficial arm-wrestling champion in the Springbok side on the 1981 tour to New Zealand? Which Springbok lock played with a glass eye? Welcome to the ultimate rugby quiz book for real rugby fans! Springbok Rugby Quiz examines the lore of rugby in an unusually entertaining way: it comprises 1001 questions and answers. Rugby lovers can now enjoy some of the most outlandish anecdotes, as well as cold, hard facts and statistics, about this game we all love. This well-researched book covers the entire spectrum of our rugby history, from the first test match in 1891, up to modern times. The book has two sections: test yourself by reading the question in the first part and then cross-check your answer in the second part. Rugby fans will certainly find more than enough challenges among the 1001 questions included here. And, as a bonus, the author also includes his Dream Team – the best players of all time united in one super team. Fun, informative and factual, this is a must-read for all rugby fans.
Molecular diagnostics is an exploding field, and recent advances in our understanding of the molecular basis of disease have provided a platform for the development of new diagnostic tests as well as tests to predict tumor behavior and potential response to targeted therapy. This textbook provides a reference and practical guide to molecular diagnostics for dermatologists and dermatopathologists. It outlines our current understanding of the molecular underpinnings of dermatologic disease, describes the appropriate use of currently available molecular tests, and explains the interpretation of these tests in the context of diagnosis and management. Tests relating to various disorders are covered, including but not confined to melanoma, genodermatoses, and infectious disease. Pitfalls are highlighted and user-friendly algorithmic approaches, presented.
This handbook features updated chapters discussing the latest and most commonly prescribed therapies for patients with moderate-to-severe psoriasis. Topics include the management of paediatric patients and patients with psoriatic arthritis.
Treatments for psoriasis often present a therapeutic challenge to physicians because, besides affecting the skin, psoriasis may be associated with various comorbidities (for instance, depression, psoriatic arthritis, Crohn’s disease and, in severe psoriasis, metabolic syndrome and cardiovascular diseases). Written by renowned experts, this volume gives a comprehensive overview of psoriasis and its various comorbidities. It describes the treatment modalities for mild and moderate-to-severe psoriasis, including topical, phototherapeutic and conventional systemic treatments (e.g. acitretine, methotrexate and cyclosporine), as well as biological therapies (e.g. alefacept, etanercept, adalimuma...
David O'Sullivan and Kevin McCallum are passionate about sport. They are fascinated by its vivid characters, heart-stopping moments and its endless drama. Over years of watching, reading and reporting on great sporting events, they have amassed a wealth of knowledge. After much deliberation, debate and pursuit of famous sports stars for personal anecdotes, they have produced this book: a fascinating collection of trivia and behind-the-scenes stories about South African sport over the years. The Penguin Book of South African Sports Trivia is the perfect companion for sports fanatics or people who just want to show off in front of their sports-mad mates. Do you know: which one-eyed Norwegian c...
The ultimate—and fun!—guide to maintaining vibrant sexual health with aging. In Never Too Late, Shannon Dowler, MD, a family physician who is also an expert on sexually transmitted diseases (STD), provides a refreshing overview of sexual education for people over 55. With the advent of dating apps, vibrant 55+ retirement communities, and sexual enhancement drugs, adults are sexually active well into their golden years. Unfortunately, the rates of STDs are dramatically increasing in older adults. In entertaining, accessible language, Dr. Dowler presents relatable patient stories and hilarious rhymes that make for an easy and fun way to learn about safe sex. This guide covers important top...
This book discusses typical skin diseases from an immunological point of view, introducing the latest immunological techniques and practices. It begins with a brief overview of the human immune system, including the basic concepts and principles as well as the general symbols used in immunology. Part Two describes the human skin as an integral part of the immune system, explaining the immunological roles of major cellular and molecular composites in the skin. Part Three illustrates typical skin diseases that have immunological involvement (immunodermatological conditions). It describes 40 skin diseases, focusing on immunological causes, pathogenesis, pattern of reaction and treatment choices...