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Nuclear Transfer Protocols: Cell Reprogramming and Transgenesis is a comprehensive review of nuclear transfer technology in vertebrates, aimed at reprogramming differentiated nuclei and effecting targeted gene transfer. The emphasis here is on providing readily reproducible techniques for the gene- tion of cloned embryos and animals in a number of key research and commercially important vertebrates. Additional chapters provide alternative cutting-edge methods for nuclear transfer, such as zona-free nuclear transfer and serial nuclear transfer. Of immense practical benefit are descriptions of procedures associated with cloning, such as in vitro maturation of oocytes, activation and culture of...
The human oocyte or egg is the rarest and most rapidly ageing cell in the body, and yet one that is essential for fertility. This book is about the development, biology and pathology of the oocyte, and new technologies to manipulate, enhance, and control fertility. These technologies are paving the way for overcoming infertility, avoiding inherited diseases, and creating genetically engineered animals from embryo stem cells and cloning. This progress would have been impossible without the myriad of scientific and technical developments covered in this book, including the ability to manipulate and fertilize oocytes in vitro. World-leading experts have contributed to the first book for many years on basic and applied science of the egg, its clinical manipulation, and its pivotal role in reproductive medicine and biology. It will be an essential reference for scientists and clinicians in reproductive medicine and animal breeding technology, and everyone involved in treating infertility.
Clinicians in the field of fertility and reproductive medicine face man and and varied problems regarding polycystic ovary syndrome. Even the name-not to mention a definition and diagnosis-has in the past conjured up much heated argument. Still, leading international researchers have here closed the gaps in the current knowledge about this disorder. They write about, and so help to create, consensus on the diagnosis, management and treatment of polycystic ovary syndrome. For its incisive distillation of all the salient theories, as well as practical therapeutic applications, Polycystic Ovary Syndrome is essential for fertility specialists and gynecologists alike.
This book explores the critical role of law in protecting - and protecting against - religious beliefs in American health care.
Nuclear Transfer Protocols: Cell Reprogramming and Transgenesis is a comprehensive review of nuclear transfer technology in vertebrates, aimed at reprogramming differentiated nuclei and effecting targeted gene transfer. The emphasis here is on providing readily reproducible techniques for the gene- tion of cloned embryos and animals in a number of key research and commercially important vertebrates. Additional chapters provide alternative cutting-edge methods for nuclear transfer, such as zona-free nuclear transfer and serial nuclear transfer. Of immense practical benefit are descriptions of procedures associated with cloning, such as in vitro maturation of oocytes, activation and culture of...
In Ethics and Human Reproduction, Christine Overall blends feminist theory and philosophical expertise to provide a coherent analysis of a range of moral questions and social policy issues pertaining to human reproduction and the new reproductive technologies. Topics covered include: sex preselection, artificial insemination, prenatal diagnosis, abortion, in vitro fertilisation and embryo transfer, surrogate motherhood, and childbirth. Throughout the book, the author examines the values and assumptions underlying common perceptions of sexuality and fertility, the status of the foetus, the value of children, the nature of parenting, and the roles of women. In so doing, she develops a feminist approach to answering questions about reproductive rights and freedoms, the value of a genetic link between mother and their offspring, the commodification of reproduction, and the effects of reproductive technologies on women and children. This book should be essential reading for anyone interested in the new reproductive technologies, biomedical ethics, and women’s health.
This book offers a unique and comprehensive outline of the ethos, the bioethics and the sexual ethics of the renowned anatomist and founder of modern geology, Niels Stensen (1638-1686). It tells the story of a student who is forced to defend himself against his professor who tries to plagiarize his first discovery, the “Ductus Stenonis”: the first performance test for the young researcher. The focal points are questions of bioethics, especially with regard to human reproduction, sexual ethics, the beginning of life and the ensoulment of the embryo, together with frontiers of pastoral care. The book delineates Stensen’s ethos as well as its medico-ethical and theological implications an...
Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of rese...
This timely and up to date new edition of Biomedicine and Beatitude features an entirely new chapter on the ethics of bodily modification. It is also updated throughout to reflect the pontificate of Pope Francis, recent concerns including ethical issues raised by the COVID-19 pandemic, and feedback from the many instructors who used the first edition in the classroom.
Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.