Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Cytotoxic Drug Resistance Mechanisms
There is now a range of cytotoxic drugs that have considerable clinical usefulness in producing responses in tumors and even, in a small proportion of cases, cure. However, the acquisition of drug resistance is a major clinical problem and is perhaps the main limiting factor in successful treatment of cancer. Thus, a tumor initially sensitive to chemotherapy will, in the majority of cases, eventually recur as a resistant tumor, which will then progress. Much of our understanding of drug resistance mechanisms comes from the study of tumor cell lines grown in tissue culture. We now understand many of the - lecular mechanisms that can lead to a cell acquiring resistance to antic- cer drugs; how...
Antiviral Methods and Protocols
This latest addition to the Methods in Molecular Medicine series, Anti- ral Methods and Protocols, is opportune because there is an increasing int- est in discovering compounds that are effective against both chronic and acute viral infections. A number of the methods described in the volume are unp- lished and their inclusion indicates the speed at which this field is moving. This volume is not a review but each chapter contains methods validated by the experts who have spent time in developing the protocols. The hallmark of this series is the comprehensive way in which the me- ods are described, which includes a list of all the reagents needed for each protocol. Of importance is the section on tips and pitfalls that the authors have discovered while developing their protocols. The manual itself is designed to be used by researchers in universities and industry who are familiar with a range of biological techniques but who want to set up quickly a novel assay system. We encourage a dialog between readers and authors, which may also result in useful collaborations.
Hemostasis and Thrombosis Protocols
Laboratory studies in hemostasis have traditionally focused on abn- malities of platelet function or the quantitative and qualitative disorders that affect the proteins involved in blood coagulation. However, over the last 10 years there has been an explosion in our understanding of the molecular bases that underlie many of the inherited and acquired disorders of hemostasis. Many of these disorders are now routinely diagnosed and assessed by methods that involve genotypic analysis. Indeed in the late 1990s the distinction between molecular methods for research and for routine diagnosis is becoming incre- ingly blurred. The techniques and approaches that are used in hemostasis are manifold an...
Management Essentials for Doctors
The only available compendium of management topics, written by practising doctors for doctors of all grades and all specialties.
HIV Protocols
The worldwide impact of infection with human immunodeficiency virus type 1 (HIV- is reflected in the cumulative number ofHIV- 1 infections, which is now predicted to exceed 40 million by the year 2000---equivalent to the n- ber of humans who perished in World War II. The medical and scientific - sponse to the HIV-1 pandemic has steadily grown since its recognition in 1981. The outlay by the United States alone for HIV research funded by the National Institutes of Health in 1997 was $1. 4 billion. Laboratory-based HIV research has brought together academic clinicians, retrovirologists, molecular biologists, and immunologists in the formation of research teams attempting to dissect the viral a...
The Air Forces Book of the F/A-18 Hornet
The F/A-18 Hornet has been in service over 20 years and has developed into and effective multi-role combat aircraft. With its array of weapon options the Hornet is capable of engaging targets on land, sea, and in the air and its ability to "swing-role" from one target type to another is impressive. The aircraft is in service with a number of air arms worldwide in both carrier-based and land-based variants.
Civil Airworthiness Certification
This publication provides safety information and guidance to those involved in the certification, operation, and maintenance of high-performance former military aircraft to help assess and mitigate safety hazards and risk factors for the aircraft within the context provided by Title 49 United States Code (49 U.S.C.) and Title 14 Code of Federal Regulations (14 CFR), and associated FAA policies. Specific models include: A-37 Dragonfly, A-4 Skyhawk, F-86 Sabre, F-100 Super Sabre, F-104 Starfighter, OV-1 Mohawk, T-2 Buckeye, T-33 Shooting Star, T-38 Talon, Alpha Jet, BAC 167 Strikemaster, Hawker Hunter, L-39 Albatros, MB-326, MB-339, ME-262, MiG-17 Fresco, MiG-21 Fishbed, MiG-23 Flogger, MiG-29 Fulcrum, S-211. DISTRIBUTION: Unclassified; Publicly Available; Unlimited. COPYRIGHT: Graphic sources: Contains materials copyrighted by other individuals. Copyrighted materials are used with permission. Permission granted for this document only. Where applicable, the proper license(s) (i.e., GFD) or use requirements (i.e., citation only) are applied.
Nighthawk F-117 Stealth Fighter
The most in-depth Stealth fighter book ever follows the development, operation, technology, testing, and history of the F-117 Nighthawk. A special section details F-117 combat operations in Panama and the Gulf War.
Sexually Transmitted Diseases
In recent years, molecular techniques have enhanced our ability to detect sexually transmitted infections and to conduct research to further our und- standing of sexually transmitted diseases. Molecular methods to quantitate pathogen load have also been shown to be useful for the management of HIV and other viral STDs. Existing laboratory manuals for the clinical microbi- ogy laboratory often do not include molecular methods for STDs. Sexually Transmitted Diseases: Methods and Protocols is intended to fill the need for a dedicated manual that covers all the fundamental aspects of molecular pro- cols for laboratory diagnosis, as well as research methodology for STDs, - cluding HIV. There are more than types of molecular techniques described in this book covering nine major sexually transmitted pathogens. Although mole- lar methods for the detection of such pathogens as Trichomonas vaginalis are available in the published literature, they have not been included since they are not yet widely used for laboratory diagnosis or research. Sexually Transmitted Diseases: Methods and Protocols is one of a series of books treating Methods Molecular Medicine, published by Humana Press.
Using The Biological Literature
"Provides an in-depth review of current print and electronic tools for research in numerous disciplines of biology, including dictionaries and encyclopedias, method guides, handbooks, on-line directories, and periodicals. Directs readers to an associated Web page that maintains the URLs and annotations of all major Inernet resources discussed in th
