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Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person's quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffold...
Cardiac tissue engineering aims at repairing damaged heart muscle and producing human cardiac tissues for application in drug toxicity studies. This book offers a comprehensive overview of the cardiac tissue engineering strategies, including presenting and discussing the various concepts in use, research directions and applications. Essential basic information on the major components in cardiac tissue engineering, namely cell sources and biomaterials, is firstly presented to the readers, followed by a detailed description of their implementation in different strategies, broadly divided to cellular and acellular ones. In cellular approaches, the biomaterials are used to increase cell retentio...
When the COVID-19 shelter-in-place order landed on Los Angeles in March 2020, professional photographer Innis Casey grabbed his camera and began snapping portraits through the windows of his quarantined neighbors. He dubbed these images 'quartraits' and before long, he was zipping across the city, shooting pictures of families, artists, professionals, and even a few celebrities such as Kate del Castillo, Eric McCormack, Seniesa "Super Bad" Estrada, and "Weird Al" Yankovic. These quartraits, it turned out, were not just mementos, they were also time capsules marking an unprecedented moment in our collective history. Curious to know more about those he captured with his lens, Innis enlisted hi...
Every day we pass a thousand people in the street or squash up against strangers in the underground. Like every city, London is teeming with life: diverse, beautiful, messy, incongruous life, and every face seen fleetingly in the crowd carries a story or two. Some are sad, some are funny, some are boring, but none are ever quite what you would guess. In Biscuits, Jenny Robins takes a look at a handful of women's stories in the city as they defy and comply with our expectations, and as they step out of the cookie cutter mould of what it means to be a woman today.
This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing. The powerful potential of hNSC to generate and repair the developing and adult CNS has been confirmed by numerous experimental in vitro and in vivo studies. The book presents methods for hNSC derivation and discusses the mechanisms underlying NSC in vitro fate decisions and their in vivo therapeutic mode of action. The long-standing dogma that the human central nervous system (CNS) lacks the ability to regenerate was refuted at the end of the 20th century, when evidence of the pr...
An assessment of climate change in Australia, including projections of Australia's future climate.
The Formula for Happiness is a self-help book which popularizes cutting-edge discoveries made by a board certified clinical psychologist about the nature of happiness and the behaviors and beliefs which enable people to become and remain happy. His groundbreaking way of understanding life and how to live has attracted worldwide attention since it was originally introduced to the scientific community in New Ideas in Psychology: an international journal of innovative theory in psychology in 1996. This is a peer reviewed journal produced by the worlds largest publisher of original scientific work and overseen by an editorial board consisting of faculty from departments of psychology in several ...
In 1953 young surgeon Robert H. Ruby began work as the chief medical officer at the hospital on the Pine Ridge Indian Reservation in South Dakota. He began writing almost daily to his sister, describing the Oglala Lakota people he served, his Bureau of Indian Affairs colleagues, and day-to-day life on the reservation. Ruby and his wife were active in the social life of the non-white community, which allowed Ruby, also a self-trained ethnographer, to write in detail about the Oglala Lakota people and their culture, covering topics such as religion, art, traditions, and values. His frank and personal depiction of conditions he encountered on the reservation examines poverty, alcoholism, the educational system, and employment conditions and opportunities. Ruby also wrote critically of the Bureau of Indian Affairs, describing the bureaucracy that made it difficult for him to do his job and kept his hospital permanently understaffed and undersupplied. These engaging letters provide a compelling memoir of life at Pine Ridge in the mid-1950s.