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This volume provides a comprehensive treatment of the Transeurasian languages. It offers detailed structural overviews of individual languages, as well as comparative perspectives and insights from typology, genetics, and anthropology. The book will be an indispensable resource for anyone interested in Transeurasian and comparative linguistics.
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Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to ...
[ The main goal of this cluster is the optimisation of the medical arts and science. In a graphical representation of human life, the lifespan or time can be shown on a horizontal axis, and the incidences of disease or health can be shown on a vertical axis. Throughout, patient exists in his personal environment, in his individual pri vate sphere. th In the late 20 century, medical arts and sciences have achieved enormous pro gress resulting in highly effective diagnosis and therapy. Today in Europe, a main concern of our society centres around non-communi cable diseases, because communicable diseases have been dramatically reduced by past intensive socio-hygienic programmes. Nevertheless, m...
The biopharmaceutical market has come along way since 1982 when the first biopharmaceutical product, recombinant human insulin, was launched. Over 120 such products are currently being marketed around the world including nine blockbuster drugs. The global market for biopharmaceuticals, which is currently valued at US$41 billion, has been growing at an impressive compound annual growth rate of 21% over the previous five years. With over one third of all pipe-line products in active development are biopharmaceuticals, this segment is set to continue outperforming the total pharmaceutical market and could easily reach US$100 billion by the end of this decade.
The last ten years have witnessed a remarkable increase in our awareness of the importance of events subsequent to transcriptional initiation in terms of the regulation and control of gene expression. In particular, the development of recombinant DNA techniques that began in the 1970s provided powerful new tools with which to study the molecular basis of control and regulation at all levels. The resulting investigations revealed a diversity of post-transcriptional mechanisms in both prokaryotes and eukaryotes. Scientists working on translation, mRNA stability, transcriptional (anti)termination or other aspects of gene expression will often have met at specialist meetings for their own resear...
While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens. This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions
Based on interviews with successful biotech entrepreneurs and high-level investors as well as case studies, this title provides a comprehensive overview of current trends in biotech funding. In particular, it illustrates the tensions between both sides based on their different backgrounds and expectations. The book outlines the various funding opportunities for the biotech industry and identifies ways for both sides to overcome their existing prejudices in order to successfully thrive in a competitive environment. A must-have for biotech entrepreneurs and investors, as well as invaluable supplementary reading for students aspiring to a career in the industry.
An interdisciplinary account of the recent advances made in understanding fundamental molecular aspects of the pre-biological and biological evolution of life.
Alexander's Alleged Wall Against Gog and Magog, often connected with the enclosure of the apocalyptic people, was a widespread theme among Syriac Christians in Mesopotamia. In the ninth century Sallam the Interpreter dictated an account of his search for the barrier to the Arab geographer Ibn Khurradadhbih. The reliability of Sallam's journey from Samarra to Western China and back (842-45), however, has always been a highly contested issue. Van Donzel and Schmidt consider the travel account as historical. This volume presents a translation of the source while at the same time it carefully looks into other Eastern Christian and Muslim traditions of the famous lore. A comprehensive survey reconstructs the political and topographical data. As so many other examples, this story pays witness to the influence of the Syriac Christian tradition on Koran and Muslim Traditions.