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Erythropoietic Stimulating Agents
The development of new erythropoietic stimulating agents (ESAs) has significantly increased in recent years. Researchers are focused on different and interesting concepts, namely, methods to increase half-life of erythropoietin (EPO), finding different routes of administration and new ESA or modified EPO molecules. Scientific literature presents evidence that EPO has other effects beyond erythropoietic stimulation. These pleiotropic effects of EPO appear to result from the existence of two different EPO receptors (EPOR) with different affinities for EPO. The discovery of new EPO actions beyond the hematopoietic system has opened a new field of investigation with these agents. Several molecul...
Marine Polysaccharides Volume 2
This book is a printed edition of the Special Issue "Marine Polysaccharides" that was published in Marine Drugs
Chronic Kidney Disease
Chronic kidney disease is an increasing health and economical problem in our world. Obesity and diabetes mellitus, the two most common cause of CKD, are becoming epidemic in our societies. Education on healthy lifestyle and diet is becoming more and more important for reducing the number of type 2 diabetics and patients with hypertension. Education of our patients is also crucial for successful maintenance therapy. There are, however, certain other factors leading to CKD, for instance the genetic predisposition in the case of polycystic kidney disease or type 1 diabetes, where education alone is not enough.
Genotoxicity
This book is designed to provide an overview of the different genotoxicants and their effects on living organisms, including humans. The contributions made by the specialists in this field of research are gratefully acknowledged. We hope that the information presented in this book will meet the expectations and needs of all those interested in the different aspects of the genotoxicity field. The publication of this book is of great importance to those scientists, pharmacologists, physicians and veterinarians, as well as engineers, teachers, graduate students and administrators of environmental programmes, who make use of these investigations to understand both the basic and applied genotoxic aspects of known and new xenobiotics, and to guide them in their future investigations.
Adiposity
This book is the second in a series of two, featuring the Adiposity - Omics and Molecular Understanding, serving as an introduction to modern views on how the adipocytes are reciprocally interacting with organ systems in order to explain the biology of the body's fat cells and how they are integrated with other organ systems, like muscle cells and the liver, in order to control the lipid metabolism in our bodies, to finally preserve a positive balance between white and brown/beige adipocyte tissues (WAT and BAT). The understanding of the "omics" of obesity will therefore enable clinicians and researchers to better pursue the untoward incidents of metabolic deviations from a defined and health-bringing homeostasis, with fully responding WAT and BAT, being able to preserve a healthy balance between fat-producing and fat-metabolizing tissues for the benefit of the host, and thus longevity (optimal health with healthy, well-functioning organ systems) throughout a lifetime.
Aspects in Dialysis
Dialysis (clearance of uremic toxins and removal of excess fluids) is a broad term for different modalities of treatment for patients with acute and end-stage kidney disease. These modalities include peritoneal dialysis, hemodialysis, hemofiltration, hemodiafiltration, and continuous renal replacement therapy for critically ill patients with acute kidney injury. Dialysis is a lifesaving measure and can be conducted in hospitals, in dialysis clinics, and at home. Recently, dialysis techniques have witnessed tremendous improvements in technology and performance. The book Aspects in Dialysis covers important aspects of dialysis-related topics and is empowered with well-established and experienced authors, who have written clear and informative chapters. It covers various aspects of dialysis modalities supported by well-established clinical studies. Aspects in Dialysis can be considered as a guide for daily practice and a reference for medical and nursing staff involved in taking care of dialysis patients.
Special Problems in Hemodialysis Patients
This book provides an overview of special cases in hemodialysis patients. Authors have contributed their most interesting findings in dealing with patients suffering of other diseases simultaneously, such as diabetes, cardiovascular disease and other health problems. Each chapter has been thoroughly revised and updated so the readers are acquainted with the latest data and observations in these complex cases, where several aspects are to be considered. The book is comprehensive and not limited to a partial discussion of hemodialysis. To accomplish this we are pleased to have been able to summarize state of the art knowledge in each chapter of the book.
Erythrocyte
Red blood cells constitute approximately 40% of the total amount of blood and 99% of shaped elements of blood. Their major function is oxygen transportation and this makes erythrocytes "the basis of life." However, as readers will see in this book, erythrocytes have a lot of different, important functions in our body. With this book, it is planned to collect current information related to "erythrocytes." The book has been divided into two sections. The first section includes information about the roles of erythrocytes in the physiological and pathophysiological processes. The second section includes information on the future perspectives of erythrocytes like their therapeutic applications in medicine. This book will be a stepping stone for scientists who are rapidly advancing their science journey.
Psoriasis
The purpose of this book is to present a comprehensive analysis of Psoriasis, a disease that affects approximately 2-3% of humanity in all countries. Psoriasis existence is surveyed since the clay tablets of Assyrians and Babylonians 3.000-5.000 years ago, thru the middle ages, the renaissance, XIX and XX centuries.
From Preconception to Postpartum
Obstetrics is evolving rapidly and finds itself today at the forefront of numerous developments. Providing selected updates on contemporary issues of basic research and clinical practice, as well as dealing with preconception, pregnancy, labor and postpartum, the present book guides the reader through the tough and complex decisions in the clinical management. Furthermore, it deepens the scientific understanding in the pathogenetic mechanisms implicated in pregnancy and motivates further research by providing evidence of the current knowledge and future perspectives in this field. Written by an international panel of distinguished authors who have produced stimulating articles, the multidisciplinary readers will find this book a valuable tool in the understanding of the maternal, placental and fetal interactions which are crucial for a successful pregnancy outcome.
