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A frequência e a quantidade de reformas promovidas no regime geral de previdência social apenas refletem e comprovam a existência da crise no sistema. A obra, fruto da dissertação de mestrado da autora, defendida em 2014, busca esclarecer, de forma atemporal - e, portanto, no contexto jurídico e filosófico -, os motivos da crise e quais seriam os meios possíveis de superá-la.
This book contains peer-reviewed papers from the Second World Landslide Forum, organised by the International Consortium on Landslides (ICL), that took place in September 2011. The entire material from the conference has been split into seven volumes, this one is the first: 1. Landslide Inventory and Susceptibility and Hazard Zoning, 2. Early Warning, Instrumentation and Monitoring, 3. Spatial Analysis and Modelling, 4. Global Environmental Change, 5. Complex Environment, 6. Risk Assessment, Management and Mitigation, 7. Social and Economic Impact and Policies.
The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and dis...
All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology while exhibiting differences in function, tissue distribution, and ligand specificity. In Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances, the authors trace the history of PPAR discovery and detail the receptor structure and its posttranslational modifications. Furthermore, endogenous ligands as well as various classes of exogenous ligands, subtype-selective, dual and pan agonists as well as antagonists, are discussed. In addition, the tissue distribution and versatile functions of PPAR subtypes in major organs are described. As PPARs play critical roles as regulators of numerous physiological as well as pathophysiological pathways, Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances aims to help researchers to develop safer and more effective PPAR modulators as therapeutic agents to treat a myriad of diseases and conditions.
This book provides a concise set of protocols for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step-by-step diagnostic assays of common neutrophil disorders. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Scientists and clinicians will find this collection an invaluable aid.
The Atlantic Forest is one of the 36 hotspots for biodiversity conservation worldwide. It is a unique, large biome (more than 3000 km in latitude; 2500 in longitude), marked by high biodiversity, high degree of endemic species and, at the same time, extremely threatened. Approximately 70% of the Brazilian population lives in the area of this biome, which makes the conflict between biodiversity conservation and the sustainability of the human population a relevant issue. This book aims to cover: 1) the historical characterization and geographic variation of the biome; 2) the distribution of the diversity of some relevant taxa; 3) the main threats to biodiversity, and 4) possible opportunities to ensure the biodiversity conservation, and the economic and social sustainability. Also, it is hoped that this book can be useful for those involved in the development of public policies aimed at the conservation of this important global biome.
The mechanism of autoantibodies cannot be explained without the detail knowledge of cytokines and interferon. These active molecules of immunology are very much dependent on each other and their function cannot be completed without their interaction towards each other. Currently, this the most updated book on this subject that helps the readers/students to upgrade their knowledge by going through chapter by chapter. Contribution by the renounced authors across the globe makes this book really unique and consider as one of the most updated textbook on this subject. This book provides a comprehensive guide to the function and types of autoantibodies and cytokines in basic and clinical field.
The three-volume set LNAI 14195, 14196, and 14197 constitutes the refereed proceedings of the 12th Brazilian Conference on Intelligent Systems, BRACIS 2023, which took place in Belo Horizonte, Brazil, in September 2023. The 90 full papers included in the proceedings were carefully reviewed and selected from 242 submissions. They have been organized in topical sections as follows: Part I: Best papers; resource allocation and planning; rules and feature extraction; AI and education; agent systems; explainability; AI models; Part II: Transformer applications; convolutional neural networks; deep learning applications; reinforcement learning and GAN; classification; machine learning analysis; Part III: Evolutionary algorithms; optimization strategies; computer vision; language and models; graph neural networks; pattern recognition; AI applications.