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Yeast Gene Analysis
Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research.Focuses on the methods most useful for the functional analysis of yeast genesAllows researcher to identify which strategy to use without having to wade through numerous recipesIncludes techniques for mutagenesis, transcript analysis, transposon tagging, and use of reporter genesDescribes the use of tools for studying post-translational modifications in yeastIncludes useful appendices with handy basic yeast recipes and WWW addresses
Biology of the Fungal Cell
What makes the fungal cell unique among eukaryotes and what features are shared? This volume addresses some of the most persistent and fascinating questions as they pertain to the growth and development of both yeast and hyphal forms of fungi. Beginning with subcellular components, the book moves on to topics including cell organization and polarity. It then moves beyond these matters to examine the cell biology of spores, the biomechanics of invasive growth, and many other subjects.
Candida and Candidiasis
The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment. • Reviews all aspects of this common fungal pathogen and its impact on human health, from the basic biology of Candida albicans to the clinical management of candidiasis. • Reviews the latest basic and clinical research, focusing on findings in genome variability, host-pathogen interactions, antifungal resistance and drug discovery, and diagnostics to foster better understanding and treatment of candidiasis. • Examines recent discoveries that have shed light on morphogenesis and the cell cycle, including how new findings on host responses may have applications for the diagnosis of blood-borne candidiasis.
The Fungal Cell Wall
This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.
Fungal Genomics
The volume is divided into four sections, the first of which, Genome Sequences and Beyond, illustrates the impact of genome-based information and techniques on research ranging from model organisms like yeast to less-studied basal fungal lineages. Furthermore, it highlights novel types of analysis made possible by multi-genome comparisons as well as the impact of genomics on culture collections and vice versa. The second section, Cell and Developmental Biology, addresses questions that are important for fungal biology, e.g. the development of fungal fruiting bodies, and biology in general, e.g. chromatin organization and circadian rhythms. The third section, Genomics for Biotechnology, covers the search for plant biomass-converting enzymes in fungal genomes and work with industrially important fungi. The fourth section, focusing on Pathogenicity, offers chapters on the genomic analysis of plant and animal/human pathogens. It illustrates how genomics at all levels, from genome to metabolome, is used to study mechanisms of the interactions of fungi with other organisms.
Fungal Allergy and Pathogenicity
The importance of fungal organisms as allergens and pathogens has been increasing considerably over the last decade. This is due, on the one hand, to a general increase in the incidence of allergies, but also to the growing number of immunocompromized individuals such as AIDS patients or transplant recipients. This book summarizes what is currently known about the allergens of Candida, Aspergillus, Cladosporium, Alternaria, Coprinus, and Psilocybe, among others, and describes the application of recombinant allergens for diagnosis and new forms of therapy. The virulence factors and defense mechanisms against Aspergillus and Candida infections are discussed as are the various causes of superfi...
Genital Infections and Infertility
This book highlights the impact of genital tract infections on female infertility, male infertility, and even veterinary infertility. A comprehensive source on genital infections essential for all infertility specialists is now at your hands.
The Biology of Fungi Impacting Human Health
Fungi have become increasingly significant determinants of human health and may cause as heavy a burden to health as viruses, bacteria and parasites. This outcome has occurred on account of the rise in diseases affecting the immune system and in the risk factors associated with advances in technologies used to treat various diseases and human conditions. These trends are no more evident than in tropical locations. This text emphasizes the biology of fungi impacting human health, with an emphasis on the Asia-Pacific region. The author draws on his own experience working in tropical Australia, Papua New Guinea and Thailand. A range of information is presented on the natural relationships of fu...
