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This book covers nanotechnology based approaches for improving the therapeutic efficacy of natural products. It critically explores lipid nanoarchitectonics, inorganic particles and nanoemulsion based tools for delivering them. With its chapters from eminent experts working in this discipline, it is ideal for researchers and professionals working in the area.
This edited book comprises of eight chapters dealing on various aspects of pharmaceutical technology for delivery of natural products. Book chapters deal with the solubility and bioavailability enhancement technologies for natural products. Emphasis has also been given on the significance of delivery strategies for improving the therapeutic efficacy of paclitaxel, galantamine and tea constituents.
Proteins suffer many conformational changes and interactions through their life, from their synthesis at ribosomes to their controlled degradation. Only folded and soluble proteins are functional. Thus, protein folding and solubility are controlled genetically, transcriptionally, and at the protein sequence level. In addition, a well-conserved cellular machinery assists the folding of polypeptides to avoid misfolding and ensure the attainment of soluble and functional structures. When these redundant protective strategies are overcome, misfolded proteins are recruited into aggregates. Recombinant protein production is an essential tool for the biotechnology industry and also supports expandi...
This compact volume is focused on an eclectic mix of biotechnological and biomedical applications of stimuli-sensitive polymeric materials. It starts with their chemical synthesis and design strategies. This is followed by discussions of their applications in microfluidics, biosensors, wound healing and anticancer therapy. Two other interesting applications covered are the design of aptamer-based smart surfaces for biological applications and use of smart hydrogels in tissue engineering. In general, it provides a snapshot of the current state-of-the-art in design and applications of smart systems at the interfaces of biological sciences.
This book has been assembled with the hope of being an authoritative, comprehensive, conceptually sound and highly informative compilation of recent advances describing the concepts of bioengineering in the field of microbiology. It comprises of seven chapters written by eminent authors in their respective fields. Topics included deal with the significant advancement of microbial technology with emphasis on drug delivery strategies for healthcare products, vaccine delivery, biotransformation approaches to generate new molecules, upstream/downstream processing of biopharmaceuticals. It serves as excellent reference material for researchers, students and academicians in the fields of biotechnology, microbiology and pharmaceutical sciences.
With the recent completion of the sequencing of the human genome, it is widely anticipated that the number of potential new protein drugs and targets will escalate at an even greater rate than that observed in recent years. However, identification of a potential target is only part of the process in developing these new next generation protein-based “drugs” that are increasingly being used to treat human disease. Once a potential protein drug has been identified, the next rate-limiting step on the road to development is the production of sufficient authentic material for testing, charact- ization, clinical trials, and so on. If a protein drug does actually make it through this lengthy an...
Nanophytomedicine is a branch of medicine that involves the application of nanomedicine-based systems to phytotherapy and phytopharmacology and the use of phytonanoparticles for biomedical applications. Nanophytomedicine covers recent advances in experimental and theoretical studies on various properties of nanoparticles derived from plant sources. This book assesses the recent advancements and applications of plant-based nanoparticles and also highlights emerging concepts of biomimetics. The book contains 24 chapters encompassing various therapeutic applications of phytochemicals derived from plants, ferns, seaweeds, and so on, mediated through nanotechnology and its allied approaches. A fervent attempt has been made to compile every significant advancement in the field of phytonanomedicine so as to accelerate its momentum in the pharmaceutical sector.
This book provides an up-to-date and rapid introduction to an important and currently active topic in graph theory. The author leads the reader to the forefront of research in this area. Complete and easily readable proofs of all the main theorems, together with numerous examples, exercises and open problems are given. The book is suitable for use as a textbook or as seminar material for advanced undergraduate and graduate students. The references are comprehensive and so it will also be useful for researchers as a handbook.
Degenerative nerve diseases are age-related, progressive and cause irreversible neurological loss that may lead too death. Chronic diseases like amylotrophic lateral sclerosis, Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease are associated with insoluble protein depositions and pose serious health challenges that may intensify in the coming decades. Current therapies only help to alleviate some of the physical or mental symptoms associated with neurodegenerative diseases, although there is currently no remedy for slow disease progression. In recent years, attempts have been made to discover a mechanism for neurodegenerative diseases and prospective treatment that may...