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Sufficient Grace
Ruth and her cousin Naomi live in a closed religious community in rural Wisconsin. But hidden dangers lurk beneath the surface of this closed frozen world. Can the girl's prayers for deliverance be answered?
Kill Your Darlings
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The Dark Wet
The Dark Wet is the first collection of short stories by Jess Huon. Rich, lyrical and deeply felt, it explores the struggle towards a sense of self and belonging, expressed in three sequences of stories: that of Jed Harp, his lover Danny Hess, and his poet sister Alexandra; of Bell and Oliver, a couple moving between Melbourne and San Francisco; and of a young woman confronting religion and sex in a Christian community in India. Drawing on a rich range of settings, from the lush Top End of Australia, to the mountains of India, and vibrant urban centres, The Dark Wet is a brutally honest portrayal of lives grasping at fluidity and transgression, and the possibility of redemption and change.
Little Sister
A noir novel, creepy and compelling At 11.06 pm, on 6 September 2001, eighteen year old Shane stands near the house of his girlfriend's father, staring at the hilt of a sword stabbed into the ground. The next morning, his best friend Will is sitting in a police station, trying to explain the tangled relationship between him, Shane, and Shane's girlfriend Eileen. Ten years later, Eileen is living in a distant city under an assumed name. As she faces the tenth anniversary of the murder that re-defined her life, she is confronted by a young woman who claims to be the little sister that Eileen abandoned, all those years ago . . . And, on the morning of 7 September 2001, a failed teacher and father wakes up on his couch, unaware of what has transpired the night before and that he alone holds the key to these past and future events. How much do we know about the people closest to us? How much do we know about ourselves? Clever, creepy and compelling, Little Sister explores ideas of absent fathers, motivation and identity, while building to an unexpected climax.
Optimal High-Throughput Screening
This concise, self-contained and cohesive book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening (HTS) experiments from a statistically sound basis. Combining ideas from biology, computing and statistics, the author explains experimental designs and analytic methods that are amenable to rigorous analysis and interpretation of RNAi HTS experiments. The opening chapters are carefully presented to be accessible both to biologists with training only in basic statistics and to computational scientists and statisticians with basic biological knowledge. Biologists will see how new experiment designs and rudimentary data-handling strategies for RNAi HTS experiments can improve their results, whereas analysts will learn how to apply recently developed statistical methods to interpret HTS experiments.
HIV-1 Integrase
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.
A Swindler's Progress
In May 1835 in a Sydney courtroom, a slight, balding man named John Dow stood charged with forgery. The prisoner shocked the room by claiming he was Edward, Viscount Lascelles, eldest son of the powerful Earl of Harewood. The Crown alleged he was a confidence trickster and serial impostor. Was this really the heir to one of Britain's most spectacular fortunes? Part Regency mystery, part imperial history, A Swindler's Progress is an engrossing tale of adventure and deceit across two worlds—British aristocrats and Australian felons—bound together in an emerging age of opportunity and individualism, where personal worth was battling power based on birth alone. The first historian to unravel...
Performativity in Art, Literature, and Videogames
This book modifies the concept of performativity with media theory in order to build a rigorous method for analyzing videogame performances. Beginning with an interdisciplinary exploration of performative motifs in Western art and literary history, the book shows the importance of framing devices in orienting audiences’ experience of art. The frame, as a site of paradox, links the book’s discussion of theory with close readings of texts, which include artworks, books and videogames. The resulting method is interdisciplinary in scope and will be of use to researchers interested in the performative aspects of gaming, art, digital storytelling and nonlinear narrative.
Enhancing Cognitive Fitness in Adults
Late life is characterized by great diversity in memory and other cognitive functions. Although a substantial proportion of older adults suffer from Alzheimer’s disease or another form of dementia, a majority retain a high level of cognitive skills throughout the life span. Identifying factors that sustain and enhance cognitive well-being is a growing area of original and translational research. In 2009, there are as many as 5.2 million Americans living with Alzheimer’s disease, and that figure is expected to grow to as many as 16 million by 2050. One in six women and one in 10 men who live to be at least age 55 will develop Alzheimer’s disease in their remaining lifetime. Approximatel...
In the Fog of the Seasons' End
A novel of great sensitivity about people in Cape Town organizing underground opposition to apartheid
