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Citizen-Driven Innovation
This guidebook aims to bring citizen-driven innovation to policy makers and change agents around the globe, by spreading good practice on open and participatory approaches as applied to digital service development in different nations, climates, cultures, and urban settings. The guidebook explores the concept of Smart Cities through a lens that promotes citizens as the driving force of urban innovation. Different models of Smart Cities are presented, showing how citizen-centric methods have been used to mobilize resources to respond to urban innovation challenges in a variety of situations, objectives and governance structures. The Living Lab approach strengthens these processes as one of the leading methods for ‘agile development’ or the rapid prototyping of ideas, concepts, products, services and processes in a highly decentralized and user-centric manner. By adopting these approaches and promoting citizen-driven innovation, cities around the world are aiming to alleviate the demand for services, increase the quality of delivery, and promote local entrepreneurship
The Elements of Big Data Value
This open access book presents the foundations of the Big Data research and innovation ecosystem and the associated enablers that facilitate delivering value from data for business and society. It provides insights into the key elements for research and innovation, technical architectures, business models, skills, and best practices to support the creation of data-driven solutions and organizations. The book is a compilation of selected high-quality chapters covering best practices, technologies, experiences, and practical recommendations on research and innovation for big data. The contributions are grouped into four parts: · Part I: Ecosystem Elements of Big Data Value focuses on establis...
Designing Data Spaces
This open access book provides a comprehensive view on data ecosystems and platform economics from methodical and technological foundations up to reports from practical implementations and applications in various industries. To this end, the book is structured in four parts: Part I “Foundations and Contexts” provides a general overview about building, running, and governing data spaces and an introduction to the IDS and GAIA-X projects. Part II “Data Space Technologies” subsequently details various implementation aspects of IDS and GAIA-X, including eg data usage control, the usage of blockchain technologies, or semantic data integration and interoperability. Next, Part III describes...
Frontiers in Anti-Infective Drug Discovery
This eBook series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the eBook series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The fourth volume of this series features 5 chapters that cover the following topics: - An overview of the incidence of neuraminadase resistance in influenza viruses in the Americas from 2004 to 2014 - Phenothiazines and derivative compounds for treating Trypanosoma cruzi infections - New antibacterial drug targets such as polysaccharide deacetylases - Improvements in aminoglycoside synthesis and biological activity (including RNA targeting) - A review of new chemotherapeutic agents against common infections.
Data Spaces
This open access book aims to educate data space designers to understand what is required to create a successful data space. It explores cutting-edge theory, technologies, methodologies, and best practices for data spaces for both industrial and personal data and provides the reader with a basis for understanding the design, deployment, and future directions of data spaces. The book captures the early lessons and experience in creating data spaces. It arranges these contributions into three parts covering design, deployment, and future directions respectively. The first part explores the design space of data spaces. The single chapters detail the organisational design for data spaces, data p...
Performances of Suffering in Latin American Migration
This book questions the reliance on melodrama and spectacle in social performances and cultural productions by and about migrants from Mexico and Central America to the United States. Focusing on archetypal characters with nineteenth-century roots that recur in the twentieth- and twenty-first centuries – heroic saviors, saintly mothers and struggling fathers, martyred children and rebellious youth – it shows how theater practitioners, filmmakers, visual artists, advocates, activists, journalists, and others who want to help migrants often create migrant melodramas, performances that depict their heroes as virtuous victims at the mercy of evil villains. In order to gain respect for the hu...
Cyclodextrin
The book is devoted to the highly versatile and potential ingredient Cyclodextrin, a family of cyclic oligosaccharides composed of ?-(1,4)-linked glucopyranose subunits. Its molecular complexation phenomena and negligible cytotoxic effects attribute toward its application such as in pharmaceuticals, cosmetics, food, agriculture, textile, separation process, analytical methods, catalysis, environment protection, and diagnostics. Efforts have also been made to concentrate on recent research outcomes along with future prospects of cyclodextrins to attract the interest of scientists from the industry and academia. The contributions of the authors are greatly acknowledged, without which this compilation would not have been possible.
The Role of MicroRNAs in Plants
Discovered in plants at the turn of the century, microRNAs (miRNAs) have been found to be fundamental to many aspects of plant biology. These small (20–24 nt) regulatory RNAs are derived via processing from longer imperfect double-stranded RNAs. They are then incorporated into silencing complexes, which they guide to (m)RNAs of high sequence complementarity, resulting in gene silencing outcomes, either via RNA degradation and/or translational inhibition. Some miRNAs are ancient, being present in all species of land plants and controlling fundamental processes such as phase change, organ polarity, flowering, and leaf and root development. However, there are many more miRNAs that are much le...
Information Technology Based Methods for Health Behaviours
Understanding and modifying health behaviors plays an important part in healthcare. The need to change behaviors applies across a range of health contexts, from individual interventions to the clinically-delivered management of chronic diseases and rehabilitation. Telehealth or virtual care technology offers many possible advantages here, including cost-efficiency, scalability, personalization, and automated high volume data collection and analysis, but success will depend on the effectiveness of the design, implementation and deployment of IT-based methods. This book, which forms part of the Global Telehealth series, includes papers presented at Global Telehealth 2019 (GT2019), a National S...
