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Contact urticaria is an immediate but transient localized swelling and redness that occurs on the skin after direct contact with an offending substance. It is caused by a variety of compounds, such as foods, preservatives, fragrances, plant and animal products, metals, and rubber latex and the mechanism by which these provoke an immediate urticarial rash at the area of contact can be divided into two categories: non-immunological contact urticaria and immunological (allergic) contact urticaria. Non-immunological contact urticaria typically causes mild localized reactions that clear within hours, e.g. stinging nettle rash. This type of urticaria occurs without prior exposure of a patient's im...
Urticaria, commonly known as ‘hives’, is a skin rash which can have allergic and non-allergic causes. This new edition is a concise guide to the diagnosis and treatment of urticaria for dermatologists and trainees. Divided into eight sections, the text begins with an introduction to the classification and diagnosis of urticaria. The following chapters cover different types of urticaria and treatment methods. The second edition has been fully updated and new topics added to provide the latest information in the field. Photographs, illustrations and tables further enhance learning.
Contact urticaria syndrome was first defined in 1975 and since then scientific interest has steadily increased. New cases are continuously being reported furnishing information on novel clinical features. A large number of compounds could be responsible for triggering the syndrome including fragrances, cosmetics, latex, preservatives, flavorings, and disinfectants. However, contact urticaria syndrome is often misdiagnosed in part due to a misinterpretation of its clinical manifestation and lack of knowledge of appropriate testing protocols and diagnostic programs. The latter have to be individualized for each patient based on the substance in question, medical history, possible concomitant d...
Filaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reaching a prevalence of up to 10%. Filaggrin proteins are crucial for skin homeostasis as their metabolites maintain skin hydration, keep the skin pH low, and provide protection against solar radiation. FLG mutation carriers suffer from dry and scaly skin and have an increased transfer of allergens and chemicals across the epidermis. Moreover, they have 10% higher serum vitamin D levels, potentially affecting the propensity to develop other diseases. FLG loss-of-function mutations represent the strongest risk factor hitherto discovered for atopic dermatitis and are major predisposing factors for related asthma and hay fever. This textbook provides comprehensive and detailed coverage of the effects of FLG mutations in health and disease (cutaneous and non-cutaneous) and also discusses the basic science, epidemiology, management, and future research areas.
Skin Allergy, An Issue of Immunology and Allergy Clinics of North America, E-Book
The foundational reference in dermal toxicology, this classic text has been completely revised to bring it up to date in the new Eighth Edition, with almost a third of its chapters being newly added. The structure of the text has also been reorganized to enable easier location of a topic of interest. With contributions from leading international ex
This handbook offers a comprehensive overview of the variety of skin issues that can arise while at work. It is meant to guide dermatologists, allergists, and industrial physicians in the successful diagnostic and management of the patients suffering from occupational skin dermatoses. It provides a look at the current modes of treatment available to practicing physicians while also offering updates on the most recent changes and advances for easy integration into practice. With an depth look at some of the more common diseases, like various urticaria and eczema as well as examining specific work places prone to exposure, this book will provide a quick and easy-to-use reference. Chapters contain patient photos and offer a multidisciplinary approach with special chapters on medical legal implications as well as exploring the minimum standards on prevention, diagnosis, and treatment as viewed worldwide. Handbook of Occupational Dermatoses is a must-have resource for dermatologists, allergists, and primary care physicians that deal with these skin issues everyday.
Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier funct...
This book explores the recent advances and integrations in molecular technology in food research platforms, which have revolutionized the way we discover and trace potential allergens in our food and drugs and how we utilize that for diagnosis and management. These different technologies for global allergenomic profiling in different kinds of food are discussed, including mass spectrometry, chromatography, and nuclear magnetic resonance. The book also addresses multiomics research with bioinformatics strategies in food allergy in terms of allergen characterization and quantitation, and covers applications in food allergy research from discovery to routine analysis.
Urticaria, commonly known as ‘hives’, is a skin rash which can have allergic and non-allergic causes. This handbook is an initiative of the Global Allergy and Asthma European Network (GA2LEN) Urticaria Centers of Reference and Excellence (UCARE). Divided into 22 sections, the text begins with an overview of urticaria, its classification, and aetiopathogenesis. The next chapters describe different types of urticaria, diagnostic measures, and therapeutic management. The final sections examine urticaria in children, in the elderly, in pregnancy and lactation, and in kidney, liver and cardiac disease. A separate chapter covers patient education material. Authored by renowned worldwide experts, the text is further enhanced by clinical images, tables and figures to assist learning.