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Immunology of HIV Infection
  • Language: en
  • Pages: 618

Immunology of HIV Infection

Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributions, divided into three sections, discuss basic mechanisms, immunopathogenesis of HIV infection, and immune-based therapies. Researchers thoroughly review vaccine-including prospects of T cell vaccine-and gene therapy for HIV infection. Additional topics include organization of HIV genes, the role of co-receptors in signaling of lymphocytes, and biological response modifiers. This reference is designed for basic and clinical researchers, internists, pediatricians, infectious disease specialists, neuropathologists, oncologists, and rheumatologists.

Successes and Challenges of NK Immunotherapy
  • Language: en
  • Pages: 540

Successes and Challenges of NK Immunotherapy

Successes and Challenges of NK Immunotherapy: Increasing Anti-tumor Efficacy describes the unique therapeutic applications of NK cells to fight cancers and eliminate the bulk and subset of cancer stem cells responsible for metastasis, relapse and recurrences. The book provides information on the development, engineering, mechanisms of action, response to various preclinical models, and applications in various clinical trials. Sections cover the development of highly engineered cytotoxic NK cells, their mechanisms of action, preclinical and clinical applications, the development and application of CAR-NK cells, and new NK-drug conjugates, also emphasizing that activated NK cells can target an...

Cytokine and Target Cell-mediated Regulation of the Maturation and Differentiation Pathways of Human Natural Killer Cells
  • Language: en
  • Pages: 584
The Tumor Immunoenvironment
  • Language: en
  • Pages: 745

The Tumor Immunoenvironment

Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor Immunoenvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development. The main goal of this publication is to provide an overview of the current knowledge on the complex and unique role of the immune system, tumor-associated inflammation and tumor-mediated immunomodulation in cancer progression in a way that allows understanding the logistics of cellular and molecular interactions in the tumor lesions.

Principles of Immunotherapy in Breast and Gastrointestinal Cancers
  • Language: en
  • Pages: 206

Principles of Immunotherapy in Breast and Gastrointestinal Cancers

  • Type: Book
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  • Published: 2024-08-20
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  • Publisher: Elsevier

Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance and New Sensitization Strategies presents updated research findings on immunotherapy, with special focus on the mechanisms of resistance of those cancer types and how to overcome them. The book discusses topics such as tumor cell-intrinsic and extrinsic mechanisms of cancer resistance to immunotherapy; the role of currently available biomarkers; strategies to overcome therapeutic resistance; sensitizing agents for cancer resistance to cell mediated immunotherapy; and Immunotherapeutic approaches, mechanisms of resistance and sensitizing strategies in gastroesophageal and biliopancreatic tum...

Insights in cancer immunity and immunotherapy: 2022
  • Language: en
  • Pages: 226

Insights in cancer immunity and immunotherapy: 2022

None

Immune Landscape of Pancreatic Cancer Development and Drug Resistance
  • Language: en
  • Pages: 284

Immune Landscape of Pancreatic Cancer Development and Drug Resistance

  • Type: Book
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  • Published: 2024-06-07
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  • Publisher: Elsevier

Immune landscape of pancreatic cancer development and drug resistance explores the advances in immune-based therapies aimed at harnessing the power of the immune system against pancreatic cancer and rewiring tumor microenvironments to eradicate pancreatic cells. With a strong focus on the development of therapeutic methods to improve the survival rates of pancreatic cancer, this book also shows the latest trends in immune targeted approaches for pancreatic cancer treatment. In 12 chapters Immune landscape of pancreatic cancer development and drug resistance discusses the current understanding of PC development and its various mutational and immune features and explore some of the new immune-...

Xenobiotics and the Gut Microbiome in Health and Disease
  • Language: en
  • Pages: 191

Xenobiotics and the Gut Microbiome in Health and Disease

None

Annual Report
  • Language: en
  • Pages: 138

Annual Report

  • Type: Book
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  • Published: 2000
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  • Publisher: Unknown

None

Immune Cell Lineage Reprogramming in Cancer
  • Language: en
  • Pages: 244

Immune Cell Lineage Reprogramming in Cancer

Topic Editor Dr. Lewis Shi received financial support from Varian Medical System, Inc. The other Topic Editors declare no competing interests with regard to the Research Topic subject.