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Farm animal proteomics 2014
Proteomics is the large-scale study of the proteome, i.e. a set of proteins being expressed in a certain fluid, tissue, organ or organism. The value of this advanced technology is being recognised in farm animal and veterinary sciences from 'farm to fork'. The potential of proteomics is unequivocal in holding a significant promise in applications such as vaccine and drug development, physiology, toxicology, animal product quality and food safety. Proteomics has been growing steadily during the last 3-4 years and, as time goes by, proteomics-based studies are more and more common, not just to scientists but to the general public as well, unravelling the full potential of this innovative techn...
Proteomics in Domestic Animals: from Farm to Systems Biology
Proteomics, like other post-genomics tools, has been growing at a rapid pace and has important applications in numerous fields of science. While its use in animal and veterinary sciences is still limited, there have been considerable advances in this field in recent years, in areas as diverse as physiology, nutrition and food of animal origin processing. This is mainly as a consequence of a wider availability and better understanding of proteomics methodologies by animal and veterinary researchers. This book provides a comprehensive, state-of-the-art account of the status of farm-animal proteomics research, focusing on the principles behind proteomics methodologies and its specific applications and offering clear example.
Protecting Children's Health in a Changing Environment
The Fifth Ministerial Conference on Environment and Health, organized by WHO/Europe and hosted by Italy, is the latest milestone in the European environment and health process, now in its twentieth year. Focused on protecting children's health in a changing environment, the Conference set Europe's agenda on emerging environmental health challenges for the years to come. The Parma Declaration is the first time-bound outcome of the environment and health process. The 53 Member States in the WHO European Region set clear targets to reduce the harm to health from environmental threats in the next decade. Safe urban settings, locally sourced food and use of ecomaterials contributed to the first e...
The Pharmacology of Taste
The Pharmacology of Taste is comprised of contributions by leading scientists from the field of chemosensory research, presented all together in the context of pharmacological principles of receptor function. The chapters cover all levels of scientific inquiry, from molecular and physiological mechanisms underlying taste signaling to its manifestation in overt behavior. The overarching objective of this volume is to inspire the application of concepts and methods of pharmacology to the study of the chemosenses.
Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins
Since the first international meeting on Vitamin B6 involvement in catalysis took place in 1962, there have been periodic meetings every three or four years. In 1990, scientists studying another cofactor, PQQ, which had already attracted the scientific community's interest for its possible involvement in amino acid decarboxylation and reactions involving amino groups, joined forces with those investigating pyridoxal phosphate-dependent enzymes. Since then, the international PQQ/quinoproteins meetings have been held jointly. In the years following the original meeting 37 years ago in Rome, Italy, the scientific gatherings have taken place in Moscow, Russia (1966); Nagoya, Japan (1967); Lening...
Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design
Chemoinformatics is paramount to current drug discovery. Structure- and ligand-based drug design strategies have been used to uncover hidden patterns in large amounts of data, and to disclose the molecular aspects underlying ligand-receptor interactions. This Research Topic aims to share with a broad audience the most recent trends in the use of chemoinformatics in drug design. To that end, experts in all areas of drug discovery have made their knowledge available through a series of articles that report state-of-the-art approaches. Readers are provided with outstanding contributions focusing on a wide variety of topics which will be of great value to those interested in the many different and exciting facets of drug design.
Time-resolved Macromolecular Crystallography
The papers presented in this volume report the striking progress X-ray diffraction has facilitated in the study of structural molecular biology. Coupled with the revival of the Laue method, the advent of high-intensity synchrotron radiation sources has made possible the rapid collection of X-ray crystallography data, thereby allowing protein and virus crystallography to progress from studies of equilibrium structures to time-resolved studies of structures at reaction stages. The book also details the many recent technological developments in physics, chemistry and biochemistry that have been critical for the full exploitation of the synchrotron Laue method in the study of dynamic events in crystals. Necessary future developments are discussed.
Biochemistry
The "Gold Standard" in Biochemistry text books, Biochemistry 4e, is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge.
