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Advances in Pharmacology
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. - This volume includes reviews on some of the hottest topics in pharmacology, including: - Multidrug resistance and the MDR1 gene in gene therapy - Regulation of calcium channels in epithelial cells - Gene therapy and vascular disease - Potential therapeutic applications for Heparin - Calcium channel blockers - Antithrombotic agents - Regulation of potassium channels in epithelial cells
Drug-induced and Iatrogenic Respiratory Disease
At the present time, 430 drugs are known to cause respiratory injury. This represents an increase of almost 200 in the last ten years, and the number is still increasing. This comprehensive, definitive reference work, with an outstanding range of international expert contributors and two of the world's leading editors, provides an essential reference for the practising respiratory physician. Key features: The text builds upon basics with a review of basic sciences. The book covers imaging, varied drug-induced interstitial lung disease including pulmonary edema and diffuse alveolar hemorrhage, acute respiratory failure, pleural involvement and upper to lower airway disease A wide range of dis...
HIV I: Molecular Biology and Pathogenesis: Clinical Applications
Although it is one of the most-widely studied viruses, many mysteries still remain about HIV. Covering the latest advances and challenges associated with clinical application of new antiviral drugs and vaccines, this revised edition is a companion to Murad: HIV-1: Molecular Biology and Pathogenesis, Second Edition. Leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. The latest developments in HIV-vaccine research New concepts in the discovery and design of novel anti-HIV drugs
Catecholamines: Bridging Basic Science with Clinical Medicine
This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.
Collaborative Innovation in Drug Discovery
Can academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the skyrocketing costs and plummeting productivity plaguing R&D, and many key products are facing patent expiration. Dr. Rathnam Chaguturu presents a case for collaboration between the pharmaceutical industry and academia that could reverse the industry's decline. Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships provides insight into the potential synergy of basing R&D in academia while leaving drug companies to turn hits into marketable products. As Founder and CEO of iDDPartners, focused on pharmaceutical in...
Treatment of Leukemia and Lymphoma
New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology. Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided. A number of experimental drug reagents currently in clinical investigation are also discussed. The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, an...
HIV: Molecular Biology and Pathogenesis: Viral Mechanisms
The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, ...
Essence of Anesthesia Practice E-Book
Highly regarded by anesthesiologists, residents, and nurse anesthetists, Essence of Anesthesia Practice, 4th Edition by Drs. Lee A. Fleisher, Michael F. Roizen, and Jeffrey Roizen, is a trusted resource for point-of-care anesthesia management. Concise, easy-to-find summaries cover a single clinical topic for both common and rare conditions. A renewed focus on diseases and drugs makes this edition even more useful when formulating anesthesia plans and mastering the core knowledge of anesthesia practice. - Features a unique, easy-to-follow, consistent format that covers a single clinical topic on each page, with a review of its problems, causes, comorbidities, and anesthesia implications. - He...
Cell Death During HIV Infection
In an effort to go beyond immune-based therapies, researchers are now considering the implications of apoptosis dysregulation during HIV-induced immunodeficiency. This work provides the first comprehensive compendium of the progress made in understanding the process of cell death related to HIV and the potential breakthroughs in treatment that offer much promise. Combining the work of more than two-dozen top researchers, this seminal volume provides clinicians and researchers with an excellent reference, while also serving as an incubator to stimulate future research. It explains the fundamental biology involved with apoptosis, explains its clinical impact in HIV, and examines the newest therapeutic approaches.
Cardiovascular Pharmacology: Heart and circulation
Cardiovascular disease remains a major cause of death and disability in developed countries and, increasingly so, in the developing world. Presented in this volume of Advances in Pharmacology are some of the most promising possibilities for treating large numbers of individuals afflicted with these conditions. - Contains up-to-date reviews of the most important emerging cardiovascular therapies written by world leaders in the field
