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This book on modelling the electrical activity of the heart is an attempt to describe continuum based modelling of cardiac electrical activity from the cell level to the body surface (the forward problem), and back again (the inverse problem). Background anatomy and physiology is covered briefly to provide a suitable context for understanding the detailed modelling that is presented herein. The questions of what is mathematical modelling and why one would want to use mathematical modelling are addressed to give some perspective to the philosophy behind our approach. Our view of mathematical modelling is broad ? it is not simply about obtaining a solution to a set of mathematical equations, but includes some material on aspects such as experimental and clinical validation.
Gastric motility disorders remain a complex clinical challenge, and inflict a substantial burden of cost and suffering on society. Gastric contractions are coordinated by an underlying electrical activity, and gastric dysrhythmias are implicated in the pathophysiology of several motility disorders. However, the significance of dysrhythmias remains uncertain, and there are few elective therapies, because current tools to investigate dysrhythmias have low reliability owing to their lack of spatial resolution. This thesis aimed to develop an improved foundation for the investigation and management of gastric dysrhythmia, by advancing and translating high-resolution (HR; multi-electrode) spatiot...
New edition of the classic complete reference book for cardiologists and trainee cardiologists on the theory and practice of electrocardiography, one of the key modalities used for evaluating cardiology patients and deciding on appropriate management strategies.
This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach.Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage.As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.
Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful i...
Suitable for advanced undergraduates & postgraduates, this book provides a definitive guide to bioinformatics. It takes a conceptual approach & guides the reader from first principles through to an understanding of the computational techniques & the key algorithms.
The Boundary Element Method is a simple, efficient and cost effective computational technique which provides numerical solutions - for objects of any shap- for a wide range of scientific and engineering problems. In dealing with the development of the mathematics of the Boundary Element Method the aim has been at every stage, only to present new material when sufficient experience and practice of simpler material has been gained. Since the usual background of many readers will be of differential equations, the connection of differential equations with integral equations is explained in Chapter 1, together with analytical and numerical methods of solution. This information on integral equatio...
AI!, in the earlier conferences (Tokyo, 1986; Atlanta, 1988, Melbourne, 1991; and Hong Kong, 1992) the response to the call for presentations at ICES-95 in Hawaii has been overwhelming. A very careful screening of the extended abstracts resulted in about 500 paper being accepted for presentation. Out of these, written versions of about 480 papers reached the conference secretariat in Atlanta in time for inclusion in these proceedings. The topics covered at ICES-95 range over the broadest spectrum of computational engineering science. The editors thank the international scientific committee, for their advice and encouragement in making ICES-95 a successful scientific event. Special thanks are...
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One of the greatest challenges for mechanical engineers is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, biomedical sciences, and medicine. This book is an opportunity for computational biomechanics specialists to present and exchange opinions on the opportunities of applying their techniques to computer-integrated medicine. Computational Biomechanics for Medicine: Models, Algorithms and Implementation collects the papers from the Seventh Computational Biomechanics for Medicine Workshop held in Nice in conjunction with the Medical Image Computing and Computer Assisted Intervention conference. The topics covered include: medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease prognosis and diagnostics, injury mechanism analysis, implant and prostheses design, and medical robotics.