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Vaccination of Special Populations: Protecting the Vulnerable
Vaccines prevent 3 million of deaths every year and are a crucial to combat antimicrobial resistance. An optimal implementation of existing vaccines could help to avert up to 1.5 million deaths as well as substantial disabilities. Indeed, vulnerable populations (VPs), including pregnant women, newborns, preterm infants, elderly and patients affected by chronic diseases are frequently undervaccinated and/or at risk of reduced vaccine efficacy, presenting a major health and economic burden to society. Vaccine development programs mainly focus on healthy populations; therefore, vaccination strategies are often based on data arising from healthy subjects.
Parasitic Diseases
Reports on schistosomiasis epidemiology and clinical features in Africa and Brazil, and development of novel drugs that affect the worm tegument, and vaccine based on excretory-secretory products and Type 2 cytokines.
Primates
Nonhuman primates (referred to here as primates) provide an invaluable source of information for a multitude of scientific fields including ecology, evolution, biology, psychology, and biomedicine. This volume addresses various topics related to primate research that includes phylogeny, natural observations, primate ecosystem, sociocognitive abilities, disease pathophysiology, and neuroscience. Topics discussed here provide a platform for which to address human evolution, habitat preservation, human psyche, and pathophysiology of disease.
Natural Killer Cells
Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.
