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Experimental Models of Epilepsy and Related Comorbidities
Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational questions about epilepsy comorbidities, are used to study the relationship between epilepsy and related comorbidities. The aim of this Research Topic was to highlight basic, clinical and interdisciplinary research involved in studying the disease and its comorbid effects. Various experimental models are used to understand the mechansims of disease and to discover newer antiepileptic drugs. These experimental models combines the input from behavioral, biochemical and molecular level including genetic.
Jasper's Basic Mechanisms of the Epilepsies
H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous e...
Neurobiology of the Epilepsies
Neurobiology of the Epilepsies – From Epilepsy: A Comprehensive Textbook, 3rd Edition, provides a concise, up-to-date review of basic sciences and the latest research advances in epilepsy. Ideal for general neurologists and neurosurgeons, epilepsy/clinical neurophysiology specialists, basic scientists, clinical researchers, and other health care providers with an interest in epilepsy, this new volume by Drs. Istvan Mody, Hal Blumenfeld, Jerome Engel, Jr., Asla Ptkänen, Ivan Soltesz, and Annamaria Vezzani offers comprehensive, authoritative coverage of this critical and complex area of the field.
Kindling 6
Proceedings of the Sixth International Conference on Kindling, featuring valuable summaries of the participants’ current cutting-edge research on the kindling of seizures and related phenomena in epilepsy.
Epilepsy: Basic principles and diagnosis
Epilepsy, Part I, Basic Principles and Diagnosis, Volume 107, in the Handbook of Clinical Neurology series offers a comprehensive review of our knowledge of the field today, including epidemiology, basic mechanisms, animal models, and topics of increasing interest such as the role of inflammation in epilepsy. It provides a comprehensive approach to description of the clinical, electrographic and imaging aspects of the epilepsies, with a clear outline of contemporary classification and the role of modern diagnostic techniques, as well as neuropsychological and psychiatric aspects of epilepsy. Chapters are authored by internationally respected neurologists with varied perspectives insuring depth to the content. A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. International list of contributors including the leading workers in the field. Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.
