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Microcirculation in Cardiovascular Diseases
  • Language: en
  • Pages: 215

Microcirculation in Cardiovascular Diseases

This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervent...

Mechanisms of Disease
  • Language: en
  • Pages: 305

Mechanisms of Disease

To reflect the changing face of undergraduate and postgraduate medical education, this new edition emphasises the principles of disease processes and their underlying mechanisms, bringing the content up to date with the latest developments from the fields of molecular and cellular biology. The focus is on describing the fundamental features of pathophysiological processes with examples to illustrate the similar mechanisms underlying apparently diverse clinical conditions. By understanding the cellular interactions in one disease area, similar principles can be applied to other disease groups and to the scientific basis of medical management and treatment strategies. Throughout, the student is encouraged to evaluate and integrate the evidence critically, developing skills for self-directed learning and the application of knowledge. To further encourage the reader to integrate the theory with clinical practice, each chapter concludes with a series of clinical scenarios and MCQs, with answers provided.

Cardiovascular Hypertrophy and Remodelling
  • Language: en
  • Pages: 64

Cardiovascular Hypertrophy and Remodelling

  • Type: Book
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  • Published: 1996-12-31
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  • Publisher: Unknown

This volume aims to explain the treatment of cardiovascular hypertrophy and remodelling to the non-specialist, and describe how they affect the outcome of hypertension, and how they are best treated.

Prehypertension and Cardiometabolic Syndrome
  • Language: en
  • Pages: 674

Prehypertension and Cardiometabolic Syndrome

  • Type: Book
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  • Published: 2018-12-06
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  • Publisher: Springer

This book sheds new light on the management of patients with borderline cardiovascular risk factors in order to prevent their progression to end organ damage. The book stimulates discussion of this poorly understood condition and lays the groundwork for developing recommendations and guidelines. While the diagnostic and therapeutic approach to full-blown diabetes, hypertension, dyslipidemia and obesity is well defined, there is still a lack of clear understanding and guidelines as far as patients with borderline conditions – especially when multiple – are concerned. Moreover, end-organ damage depends on several factors, including genetic factors, making it difficult to predict its extent...

Manual of Hypertension of The European Society of Hypertension
  • Language: en
  • Pages: 403

Manual of Hypertension of The European Society of Hypertension

  • Type: Book
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  • Published: 2008-09-11
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  • Publisher: CRC Press

The European Society of Hypertension Guidelines are imparted throughout the text in order for the reader to achieve 'better practice.' The data provided is all evidence-based and clearly referenced. Professor Guiseppe Mancia is a leading light on the management and treatment of hypertension and is particularly expert on the angiotensin II recept

Arterial Disorders
  • Language: en
  • Pages: 426

Arterial Disorders

  • Type: Book
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  • Published: 2015-03-19
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  • Publisher: Springer

As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised. ​

Profiling Hackers
  • Language: en
  • Pages: 640

Profiling Hackers

  • Type: Book
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  • Published: 2008-12-11
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  • Publisher: CRC Press

Complex and controversial, hackers possess a wily, fascinating talent, the machinations of which are shrouded in secrecy. Providing in-depth exploration into this largely uncharted territory, Profiling Hackers: The Science of Criminal Profiling as Applied to the World of Hacking offers insight into the hacking realm by telling attention-grabbing tales about bizarre characters that practice hacking as an art. Focusing on the relationship between technology and crime and drawn from the research conducted by the Hackers Profiling Project (HPP), this volume applies the behavioral science of criminal profiling to the world of internet predators. The authors reveal hidden aspects of the cyber-crim...

Cardio-Renal Clinical Challenges
  • Language: en
  • Pages: 237

Cardio-Renal Clinical Challenges

  • Type: Book
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  • Published: 2014-11-12
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  • Publisher: Springer

​​​​​​​​In modern medicine, the aging population is prone to many simultaneous cardiovascular (CV) risk factors which often produce co-incident pathology. Nowhere is this more obvious than in the interaction between Chronic Kidney Disease (CKD), Diabetes and diverse CV diseases (CVD). This is a complex and challenging area, as the presence of CKD/diabetes promotes CVD while also complicating its treatment. The emergence of CKD as a public health priority is one of the most challenging problems of modern medicine. It is now solidly established that renal dysfunction portends a high risk for cardiovascular disease. Cardiovascular diseases remains the main cause of death in west...

Manual of Hypertension of the European Society of Hypertension, Third Edition
  • Language: en
  • Pages: 1377

Manual of Hypertension of the European Society of Hypertension, Third Edition

  • Type: Book
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  • Published: 2019-06-06
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  • Publisher: CRC Press

The Manual of Hypertension of the European Society of Hypertension reflects emerging concepts that have the potential to impact diagnostic and therapeutic approaches to hypertension. Updating all material, this new edition also delves into a number of areas that have received heightened interest in recent years or have become a matter of debate due to the controversial interpretation of the available data. FEATURES Reflects emerging concepts impacting diagnostic and therapeutic approaches Explores background, history, epidemiology, and risk factors Describes pharmacological, nonpharmacological, and medical treatments Examines hypertension in special populations and treatment

The Renin-angiotensin System
  • Language: en
  • Pages: 668

The Renin-angiotensin System

  • Type: Book
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  • Published: 1993
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  • Publisher: Mosby

This is a detailed, state-of-the-art account of the renin-angiotensin system. It covers all aspects of the subject by describing contemporary research whilst also emphasising historical perspectives. Volume One considers scientific aspects such as structure, function, evolution, biochemistry and genetics; Volume two details the pathophysiology of the system and describes how knowledge of the RAS is being applied practically to therapeutic techniques. Each chapter is fully illustrated as appropriate: tables, algorithms, graphs, conceptual artworks and black and white photographs are all used. Where colour photographs are included, they are presented in a plate section at the front of the volume.