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Antibiotics
A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folat...
Antibiotics
Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.
Antibiotics
Antibiotics; Origin, Nature and Properties, Volume II focuses on the principles of the classification of antibiotic substances. This volume is divided into four main topics—antibiotics produced by Fungi imperfecti, antibiotics produced by fungi belonging to the basidiomycetes and ascomycetes, antibiotics produced by lichens and algae, and antibiotics from higher plants. The antibiotics covered in this book include penicillin, viridicatin, cyclopaldic acid, cephalosporin P, bongkrek acid, chlamydosporine, and flammulin. The diploicin, chlorellin, chlorophorin, ethyl gallate, anacardic acid, and echinacosid are also described. Other antibiotics include the tuberosine, antifungal substance from field corn, fulvoplumerin, plumericin, and chinoc acid. This publication is recommended for pharmacists and specialists interested in the classification of antibiotics.
Antibiotics
Antibiotics, the potent medicines that fight bacterial infections, can save lives. We take these miracle substances for granted, but theyve truly transformed medicine as this accessible guide relates. The major discoveries of bacteria destroyers, including penicillin, are highlighted as well as their impact. Each impressive chapter explains the most important aspects of antibiotics, including their variety, how theyre given, their side effects, and their limitations. Also addressed, ripped from the headlines, is the current controversy surrounding vaccines. Information about antibiotic resistance, misuse, superbugs, and the future of antibiotics will make readers feel like medical professionals!
Antibiotics
Antibiotics are truly miracle drugs. As a class, they are one of the only ones that actually cure disease as opposed to most drugs that only help relieve symptoms or control disease. Since bacteria that cause serious disease in humans are becoming more and more resistant to the antibiotics we have today, and because they will ultimately become resistant to any antibiotic that we use for treatment or for anything else, we need a steady supply of new antibiotics active against any resistant bacteria that arise. However, the antibiotics marketplace is no longer attractive for large pharmaceutical companies, the costs of development are skyrocketing because of ever more stringent requirements by the regulatory agencies, and finding new antibiotics active against resistant strains is getting harder and harder. These forces are all combining to deny us these miracle drugs when we need them the most. I provide a number of possible paths to shelter from this perfect storm.
Antibiotics
Virtually everyone has taken antibiotics. They can be lifesavers -- and they can be useless. What are they? How are they used? And what happens as the effectiveness of antibiotics continues to decline? Antibiotics: What Everyone Needs to Know® examines the personal and societal implications of our planet's most important -- and frequently misused -- medications. In a question-and-answer format, it unpacks the most complicated aspects of this issue, including: How antibiotics are used (and overused) in humans, plants, and livestock; the causes and consequences of bacterial resistance to antibiotics; how the globalized world enables antibiotic resistance to spread quickly; and the difficult decisions ahead for both medical care and the food system. Grounded in the latest scientific research and crafted for general readers, Antibiotics: What Everyone Needs to Know® offers a clear-eyed overview of where we are, and what the future holds, as antibiotics lose their power.
Antibiotics
In this translation of the Italian second edition, the authors provide a comprehensive account of the current knowledge on antibiotics. They concisely describe how various scientific disciplines are involved in antibiotics research, development, and use. Their work also discusses the industrial and clinical development of new antibiotics, as well as the questions and controversies related to the function of antibiotics in nature. Antibiotics is richly illustrated with clear chemical structures, drawings, diagrams, and synoptical tables.
Antibiotics
Amazing medical breakthroughs are made every day. In the past decades, medical researchers have cured diseases that were once deadly and devised new methods to heal that were once unimaginable. This title follows the development of antibiotics, including premodern forerunners to antibiotics, groundbreaking discoveries and the doctors who made them, and where the science is heading in the future. Learn how antibiotics work and why scientists need to continually discover new drugs. Sidebars, full-color photos, a glossary, and well-placed graphs, charts, and maps, enhance this engaging title. Aligned to Common Core Standards and correlated to state standards. Essential Library is an imprint of Abdo Publishing, a division of ABDO.
Antibiotics
A lucky laboratory accident led to the discovery of penicillin, the first antibiotic. In the mid-20th century, many people thought that antibiotics would end bacteria-caused diseases forever. Today, though, overuse of antibiotics has made so many kinds of bacteria resistant to these drugs that some experts think antibiotics will soon be useless.
WHO Model Prescribing Information
This book provides independent clinical information on essential drugs, including details of dosage, uses, contraindications and adverse effects. It is intended as source material for adaptation by national authorities, in particular developing countries, that which to produce drug formularies, data sheets and teaching materials.
