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Thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology, DeGroot's Endocrinology, 8th Edition, remains the comprehensive, international reference of choice for today's endocrinologists and fellows. A full peer review of the previous edition, conducted by a largely new group of renowned editors, was used to update this trusted, two-volume resource. In-depth coverage of both basic and clinical aspects of endocrinology and up-to-date information on the treatment and management of endocrine disorders are provided by a diverse group of expert contributors from six continents. A full-color format and helpful algorithms summarize clinical decision-making and pract...
This issue of Endocrinology and Metabolism Clinics, edited by Dr. Alice Levine, is devoted to Adrenal Disease. This issue will be broken down into 3 sections: Overview of Adrenal Cortical Development, Steroidogenesis, Comparative Anatomy and Molecular Pathophysiology; Benign Adrenal Tumors; and Adrenal Cortical Carcinoma. Articles in this issue include: Adrenal Cortical Zonal Development; Adrenal Steroidogenesis and Congenital Adrenal Hyperplasia; Animal Models of Adrenocortical Tumorigenesis; Genetics of Adrenal Cortical Tumors; Adrenal Incidentalomas; Aldosteronomas – Challenges in Diagnosis and Management; Mild Hypercortisolism Due to Adrenal Adenomas – Definitions and Therapeutic Options; Management of Adrenal Tumors in Pregnancy; Pathology of ACC; Diagnosis and Medical Management of ACC; and Surgical Management of ACC.
Genetic Steroid Disorders, Second Edition targets adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologists. It is designed to assist these specialists in the diagnosis and treatment of steroid disorders. This revision includes a new chapter on "Gonadotropins, Obesity and Bone" and new research on non-invasive prenatal diagnosis with cell-free DNA. Chapters are thoroughly updated covering steroid disorders, the genetic bases for the disorder and case presentations, This definitive reference belongs in every medical library! - Presents a comprehensive, translational look at all aspects ...
Adrenocortical tumors (ACT) are common neoplasms, with a prevalence that increases with age, reaching a peak of 6% after 60 years. Most are benign cortical adenomas (ACA). Their malignant counterparts, adrenocortical carcinomas (ACC), are rare and are usually associated with a dismal prognosis. The genetic basis of adrenocortical tumorigenesis is not completely understood, but is thought to be a multistep process. Over the past two decades many molecular aspects of ACT tumorigenesis have been uncovered, especially after the elucidation of the molecular basis of genetic syndromes of which ACTs are a feature. More recently, genome-wide expression profiles and animal models have provided new insights into the explanation of this complex process. Many of the key genes and pathways have been elucidated and are the current focus of therapeutic intervention. Integrated pangenomic and other global analyses will be done in the coming years and promise to advance our understanding of adrenocortical tumorigenesis to a higher level.
The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research. Part A contains abstracts 1-3062 accepted for the 2017 meeting.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Now updated online for the life of the edition, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 11th Edition keeps you up to date in this fast-changing field. Every quarter, your eBook will be updated with late-breaking developments in oncology, including new drugs, clinical trials, and more.
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting l...
The definitive guide to genetic bone disorders, now revised and expanded with glossy photographs and radiographs "Brilliantly written and produced and deserves to be on the shelves of all pediatric radiologists. It should also be available to geneticists, counselors, and pediatricians." --Radiology This updated and expanded fourth edition of Bone Dysplasias presents age-related radiographs, photographs and clinical guidelines for more than 250 rare constitutional skeletal diseases. Focusing on diagnostically essential imaging and clinical features, each chapter is supplemented with prognostic and therapeutic information, a guide to differential diagnoses, and a short list of the most relevant publications. Organized in accordance with the most recent International Nosology and Classification of Genetic Skeletal Disorders, this new Bone Dysplasias distills the insights of a small, world-class author team on diagnosis and clinical approaches to this most difficult class of disorders.