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Molecular Detection of Human Viral Pathogens
Despite being recognized and fought against over countless centuries, human viral pathogens continue to cause major public health problems worldwide-killing millions of people and costing billions of dollars in medical care and lost productivity each year. With contributions from specialists in their respective areas of viral pathogen research, Mol
Epitranscriptomics
This book reviews a novel and exciting field of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism’s cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Ac...
Prognostic and Therapeutic Applications of RKIP in Cancer
Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students.
Identifying Clinically Relevant Transcriptional Signatures and Methylation Profiles in the Course, Treatment and Outcome of Colorectal Cancer
Despite major efforts to stratify colorectal cancer patients, only a few prognostic and predictive biomarkers are still used in clinical practice. Inter- and intratumoral heterogeneity is one of the factors influencing strategies for biomarker identification and their implementation in clinical decisions. Recent characterization of consensus molecular subtypes has demonstrated the importance of transcriptome analysis, but the need for in-depth analysis considering other parameters has become apparent. Strategies to study and understand inter- and intratumoral heterogeneity at the tumor tissue level, focusing on gene expression, transcriptomics, and epigenetics, may improve colorectal cancer classification and lead to the identification of biomarkers of prognostic and predictive importance to complement genetics. They could lead to a better understanding of the causes of treatment failure and disease recurrence and thus to new possibilities for patient stratification. Liquid biopsy is currently an effective strategy to capture tumor heterogeneity in non-invasive monitoring of disease progression and recurrence.
Metastasis: From Cell Adhesion and Beyond
This eBook consists of a collection of articles focused on fundamental processes of cancer cell metastasis, such as cell-Extracellular matrix adhesions, epithelial-to-mesenchymal transition (EMT) and lymph node metastasis as well as on upcoming research fields including the effects of biomechanical factors, the use of analytical and statistical tools and experimental techniques to further understand and characterize the invasive and metastatic potential of tumors.
E-Health Technologies and Improving Patient Safety: Exploring Organizational Factors
Advancements in technology regularly influence the healthcare field and developing aspects on medical patient safety. Implementing electronic health records, decision support systems, and computerized physician order entry systems reduces risk in the potential for e-health to make errors leading to adverse events. E-Health Technologies and Improving Patient Safety: Exploring Organizational Factors presents an overview on information and communication technologies and addresses the impacts on the field of both patient safety and e-health. This book offers insightful perspectives and concentrated research on concepts related to these areas, as well as issues and current trends in patient safety in e-health.
Encyclopedia of Information Science and Technology, Third Edition
"This 10-volume compilation of authoritative, research-based articles contributed by thousands of researchers and experts from all over the world emphasized modern issues and the presentation of potential opportunities, prospective solutions, and future directions in the field of information science and technology"--Provided by publisher.
Medical Advancements in Aging and Regenerative Technologies: Clinical Tools and Applications
"This book translates basic science discoveries into regenerative therapies with the application of clinical tool in aging and tissue regeneration"--
