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A great deal of knowledge about eosinophilic lung diseases has been gained in the last few years, but unanswered questions concerning eosinophil biology still remain. It is in this context that this Monograph was developed. Broad in scope, the book bases its approach to the management of eosinophilic lung diseases on a fundamental understanding of eosinophil biology in health and disease. State-of-the-art reviews written by world-leading authorities and up-and-coming stars in the field take the reader on a journey through the different eosinophilic lung diseases. This Monograph will ensure the practicing clinician is better equipped to recognise and treat patients with eosinophilia, as well as appreciate the advances coming in the near future.
A cutting-edge collection of readily reproducible techniques for the isolation, culture, and study of activation and signaling in human mast cells. These methods take advantage of the latest advances in molecular biology, technology, and information science. They include methods for the identification of mast cells, the development of mast cells in vitro, the study of mast cell signaling and gene expression, and the measurement of mast cell expression of inflammatory mediators. Additional chapters cover methods for studying mast cell interactions with other cell types (endothelial cells, fibroblasts, and B cells), the roles of mast cells in host defense, and mast cell apoptosis.
Based upon global data and following on from Lockdown: Social Harm in the COVID-19 Era, this book discusses the rise of surveillance capitalism and new forms of control and exclusion throughout the Covid-19 pandemic. It particularly addresses the use of vaccine passports, mandates and the new forms of capital extraction and political control that emerged throughout the pandemic. The book also explicates how the ‘vaccine hesitant’ became marginalized in both mainstream discourse and through regulatory interventions. Whilst the book addresses the wider political economy within which so-called ‘anti-vaxxers’ were ostracized, it also explores the complex nature of their sentiments. The b...
#1 on AMAZON, and a NEW YORK TIMES, WALL STREET JOURNAL, USA TODAY and PUBLISHERS WEEKLY NATIONAL BESTSELLER Pharma-funded mainstream media has convinced millions of Americans that Dr. Anthony Fauci is a hero. He is anything but. As director of the National Institute of Allergy and Infectious Diseases (NIAID), Dr. Anthony Fauci dispenses $6.1 billion in annual taxpayer-provided funding for scientific research, allowing him to dictate the subject, content, and outcome of scientific health research across the globe. Fauci uses the financial clout at his disposal to wield extraordinary influence over hospitals, universities, journals, and thousands of influential doctors and scientists—whose ...
„Doktor Joseph Goebbels napisał, że: „Kłamstwo wypowiedziane raz pozostaje kłamstwem, ale kłamstwo wypowiedziane tysiąc razy staje się prawdą”. Bardzo wiele takich kłamstw słyszymy od Fauciego i jego popleczników. Robert F. Kennedy Jr. ukazuje całe dziesięciolecia szerzenia nieprawdy.”– Luc Montagnier, laureat Nagrody Nobla Książka obszernie i bezpośrednio opisuje kontrowersje wokół osoby doktora Anthony’ego Fauciego, dyrektora National Institute of Allergy and Infectious Diseases (NIAID). Według jej autora Fauci w trakcie swojej kariery stosował manipulacje naukowe i finansowe, a także naruszał prawo, aby uzyskać kontrolę nad światową polityką zdrowotn...
Clearance of apoptotic cells is essential for proper development, homeostasis and termination of immune responses in multicellular organisms. Thus, cellular and molecular players taking part in the sequential events of this process are of great interest. Research in the last 20 years has indicated that specific ligands and receptors take part in the attraction of immune cells toward apoptotic targets and in the interactions between apoptotic cells and professional as well as non-professional phagocytes that engulf them. Moreover, phagocytosis of apoptotic cells (efferocytosis) leads to significant phenotypic changes in the engulfing cells suggesting that it is a major fate-determining event ...