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Image-Guided Hypofractionated Stereotactic Radiosurgery
• Discusses the pros and cons of hypofractionated SRT compared to single-fraction radiosurgery, providing a deeper understanding of radiosurgery and radiobiology. • Explains the toxicity and adverse effects of hypofractionated SRT including the 24 Gy in 2 spine SBRT fractionation scheme, aiding practitioners in communicating the risks and benefits of treatment and in obtaining their patients’ consent. • Outlines the current standards for safe practice, including checklists for implementation. • Explores new technologies for brain and spine tumours including LITT, MR Guided Focussed Ultrasound and Zap technology with chapters authored by well-recognized experts in the radiation, oncology, and neurosurgery communities, this book delivers a level of technological and clinical detail not available in journal papers.
Intracranial and Spinal Radiotherapy
This book is a practical, up-to-date guide to the treatment of patients with brain and spinal tumors. Leading experts in the field explain treatment techniques in detail, highlighting key considerations in the use of external beam radiation therapy, intensity-modulated radiation therapy, particle therapy, radiosurgery, and stereotactic body radiation therapy. Specific recommendations are described for different tumor types, and helpful information provided on other important issues, such as the interaction of radiotherapy and systemic therapy and the avoidance of treatment complications. With the development of modern technology, highly conformal radiotherapy techniques have become more complicated, yet also more widely employed. This book will equip readers with the knowledge required to set up practices to deliver quality brain and spinal radiation therapy appropriate to each patient. It will be of benefit to radiation oncologists, clinical oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses as well as medical oncologists and surgical oncologists with an interest in radiotherapy.
Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy
This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorab...
Contemporary Management of Intracranial Metastatic Disease
The development of intracranial metastatic disease (IMD) complicates the course of 20% of patients with cancer. Despite improvements in patient survival with more aggressive treatment options as compared to the prior standard of palliative whole brain radiation, outcomes for patients who develop IMD remain dispiriting. There is need to celebrate our advances; but a major collaborative multidisciplinary effort is needed to push the field to achieve more meaningful survival benefits for our patients with IMD. In this Research Topic collection, we have assembled work detailing the latest innovations in brain metastases imaging and management, spanning from minimally invasive surgery to immunotherapy. We hope that you find it a valuable resource.
Adult CNS Radiation Oncology
This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. Th...
Behavioural Neuroscience
Brain and behaviour are intrinsically linked. Animals demonstrate a huge and complex repertoire of behaviours, so how can specific behaviours be mapped onto the complicated neural circuits of the brain? Highlighting the extraordinary advances that have been made in the field of behavioural neuroscience over recent decades, this book examines how behaviours can be understood in terms of their neural mechanisms. Each chapter outlines the components of a particular behaviour, discussing laboratory techniques, the key brain structures involved, and the underpinning cellular and molecular mechanisms. Commins covers a range of topics including learning in a simple invertebrate, fear conditioning, taste aversion, sound localization, and echolocation in bats, as well as more complex behaviours, such as language development, spatial navigation and circadian rhythms. Demonstrating key processes through clear, step-by-step explanations and numerous illustrations, this will be valuable reading for students of zoology, animal behaviour, psychology, and neuroscience.
Bone and Brain Metastases
Bone and brain metastasis are of great importance because they can profoundly affect a patient's quality of life and function. Complications of metastasis include pain, neurologic dysfunction and, in cases of bone metastasis, fractures and resulting loss of mobility. In particular for brain metastasis, personality and cognitive changes can affect the patient's performance status which can jeopardise further systemic therapies aimed at prolonging survival. Ultimately, both conditions are very frightening for the cancer patient and their families. This book highlights the importance of expertise in the management of bone and brain metastasis.
Clinical Insights
The ten chapters of this book provide a concise overview of the various aspects of stereotactic body radiation therapy for non-small-cell lung cancer (NSCLC), including general, radiobiological, technical and clinical issues.
AOSpine Masters Series Volume 1: Metastatic Spinal Tumors
A focused guide from the world's experts on metastatic spine tumors" This first volume in the AOSpine Masters Series integrates the expertise of oncologists and radiology interventionalists with that of master spine surgeons, all of whom are actively involved in the care of patients with metastatic spine tumors. The book provides expert guidance to help clinicians make the right treatment decisions and provide the best care for their patients. Chapter topics range from evaluation and decision-making principles to a spectrum of non-operative and operative treatment options that have been rapidly evolving over the past decade. Key Features: Editors are internationally-recognized authorities on...
