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Mesenchymal Stromal Cells
Mesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress has become exponential over the past decade due mainly to the broad therapeutic potential of these cells. However, MSC studies have also been subject to controversy and increasing scrutiny as new mechanisms of action are reported and ever-expanding therapeutic applications pursued. In this book, leading authorities from all over the world, who are actively involved in this field, provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with MSCs. This ...
Cambridge Medical Reviews: Haematological Oncology: Volume 3
Haematological Oncology serves as a regular forum for the evaluation and dissemination of new information in this field and the topics selected for review range from basic science to clinical applications. The papers in Volume 3 cover the epidemiology of lymphoma; viral etiology of Hodgkin disease; cytogenetics of ALL; fungal infection; peripheral blood stem cell transplantation; conventional and aggressive treatment of myloma; and the laboratory aspects of myclodysplasia and differentiation therapy. This up-to-date review of the current state of research in hematological oncology will be an important source of information and knowledge.
Regenerative and Cell Therapy
This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasizes clinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur throughout the body even in highly differentiated organs like the heart and the neuronal system. It provides examples of breakthroughs in the clinical implementation of adult stem cell therapy.
Experimental and Applied Immunotherapy
Immunotherapy is now recognized as an essential component of treatment for a wide variety of cancers. It is an interdisciplinary field that is critically dependent upon an improved understanding of a vast network of cross-regulatory cellular populations and a diversity of molecular effectors; it is a leading example of translational medicine with a favorable concept-to-clinical-trial timeframe of just a few years. There are many established immunotherapies already in existence, but there are exciting new cancer immunotherapies just on the horizon, which are likely to be more potent, less toxic and more cost effective than many therapies currently in use. Experimental and Applied Immunotherap...
